Efficient Synthesis of Octahydro-5H-Dibenz[b,f]azepin-10-one Derivatives by an Easy Two-Step Route from Available 2-Carbethoxymethyl Cyclohexanone and Anilines

Alirio Palma; Jacqueline J. Barajas; Vladimir V. Kouznetsov; Elena Stashenko; Ali Bahsas; Juan Amaro-Luis

doi:10.2174/1570178043400767

ISSN: 1570-1786
E-ISSN: 1875-6255

Efficient Synthesis of Octahydro-5H-Dibenz[b,f]azepin-10-one Derivatives by an Easy Two-Step Route from Available 2-Carbethoxymethyl Cyclohexanone and Anilines
Authors: Alirio Palma¹, Jacqueline J. Barajas², Vladimir V. Kouznetsov³, Elena Stashenko⁴, Ali Bahsas⁵ and Juan Amaro-Luis⁶
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¹ Laboratorio de Sintesis Organica Fina, Centro de Investigación en Biomoleculas, Escuela de Quimica, Universidad Industrial de Santander, A.A. 678, Bucaramanga, Colombia ² Laboratorio de Sintesis Organica Fina, Centro de Investigación en Biomoleculas, Escuela de Quimica, Universidad Industrial de Santander, A.A. 678, Bucaramanga, Colombia ³ Laboratorio de Sintesis Organica Fina, Centro de Investigación en Biomoleculas, Escuela de Quimica, Universidad Industrial de Santander, A.A. 678, Bucaramanga, Colombia ⁴ Laboratorio de Sintesis Organica Fina, Centro de Investigación en Biomoleculas, Escuela de Quimica, Universidad Industrial de Santander, A.A. 678, Bucaramanga, Colombia ⁵ Laboratorio de Sintesis Organica Fina, Centro de Investigación en Biomoleculas, Escuela de Quimica, Universidad Industrial de Santander, A.A. 678, Bucaramanga, Colombia ⁶ Laboratorio de Sintesis Organica Fina, Centro de Investigación en Biomoleculas, Escuela de Quimica, Universidad Industrial de Santander, A.A. 678, Bucaramanga, Colombia
Source: Letters in Organic Chemistry, Volume 1, Issue 3, Jul 2004, p. 261 - 263
DOI: https://doi.org/10.2174/1570178043400767
- Available online: 01 Jul 2004

Abstract

Synthesis of new octahydrodibenz[b,f]azepin-10-one derivatives by a two-step synthetic route based on 2-carbethoxymethyl cyclohexanone reactivity is reported.

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2004-07-01

2025-05-29

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Article Type: Review Article

Keyword(s): cis/trans isomers; partially reduced dibenz[b,f]azepin-10-ones; reductive amination

Efficient Synthesis of Octahydro-5H-Dibenz[b,f]azepin-10-one Derivatives by an Easy Two-Step Route from Available 2-Carbethoxymethyl Cyclohexanone and Anilines

Abstract

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