The Role of Kinetics in High Throughput Screening for Drugs

Agustina Gomez-Hens; M. P. Aguilar-Caballos

doi:10.2174/1574088054583363

ISSN: 1574-0889
E-ISSN:

The Role of Kinetics in High Throughput Screening for Drugs
Authors: Agustina Gomez-Hens¹ and M. P. Aguilar-Caballos²
View Affiliations Hide Affiliations

Affiliations: ¹ Department of Analytical Chemistry, Faculty of Sciences, “Marie Curie” Building Annex, Campus of Rabanales, University of Cordoba, 14071-Cordoba, Spain. ² Department of Analytical Chemistry, Faculty of Sciences, “Marie Curie” Building Annex, Campus of Rabanales, University of Cordoba, 14071-Cordoba, Spain.
Source: Frontiers in Drug Design & Discovery, Volume 1, Issue 1, Jan 2005, p. 167 - 195
DOI: https://doi.org/10.2174/1574088054583363
- Available online: 01 Jan 2005

Abstract

A systematic study of the incidence of kinetics in high throughput screening for drug design and discovery is presented and discussed. This study includes dynamic aspects of the techniques and assays used in this complex research field, kinetic methods applied to the selection of drug candidates, and recent advances in the elucidation of drug-receptor interaction mechanisms and in high throughput pharmacokinetic screening.

Article metrics loading...

/content/journals/fddd/10.2174/1574088054583363

2005-01-01

2024-11-26

From This Site

/content/journals/fddd/10.2174/1574088054583363

dcterms_title,dcterms_subject,pub_keyword

-contentType:Contributor -contentType:Concept -contentType:Institution

10

5

Full text loading...

/content/journals/fddd/10.2174/1574088054583363

Article Type: Review Article

Keyword(s): adme; chromatography; combinatorial technologies; drug-drug interactions; electrophoresis; genome; hts assays; luminescent; pharmacokinetic; proteome

The Role of Kinetics in High Throughput Screening for Drugs

Abstract

From This Site

Most Read This Month