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2000
Volume 20, Issue 9
  • ISSN: 1871-5303
  • E-ISSN: 2212-3873

Abstract

Background: There is a need for rapid and accurate diagnostic biomarker for diagnosis of Salmonella fever. Aims: The aim of the present study was to assess the importance of procalcitonin (PCT), Soluble Triggering Receptors expressed on Myeloid Cells 1 (sTREM1) and C- reactive protein (CRP) in the diagnosis of enteric fever with positive blood culture for S.typhi. Methods: Blood samples were withdrawn from 200 patients with suspected enteric fever and subjected for the determination of CRP, PCT and sTREM-1. Results: The sensitivity and specificity for PCT cut off were 97.7% & 82.5%, for CRP the sensitivity and specificity were 95.3% and 77% and for s-TREM-1 the sensitivity and specificity were 95.3% & 77%. Conclusion: S-TREM-1 may be considered as a novel biomarker for the diagnosis of enteric fever with good sensitivity and specificity.

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/content/journals/emiddt/10.2174/1871530320666200206120151
2020-11-01
2025-05-23
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/content/journals/emiddt/10.2174/1871530320666200206120151
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  • Article Type:
    Research Article
Keyword(s): blood culture; CRP; ELISA; Enteric fever; PCT; sTREM1
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