Recent Patents on Drug Delivery & Formulation - Volume 8, Issue 2, 2014

Subconjunctival/episcleral, intrascleral, and suprachoroidal routes of drug delivery for treatment of posterior segment eye diseases have become more feasible and popular in the past few years. These routes have the advantage of bypassing the main barriers to topical drug penetration, the ocular surface epithelium, the conjunctivallymphatics, and in the case of deep intrascleral and suprachoroidial delivery, the sclera barrie Read More

Lozenges, the small medicated candies that dissolve slowly in the mouth have always been a favoured delivery system, particularly for drugs meant for relieving sore throats and cold symptoms. This predilection can be attributed mainly to their ability to keep the naso-pharyngeal mucosa moist, enhance the swallowing reflex and provide longer contact time of the drug with the naso-pharyngeal mucosa. A number of innovative te Read More

Microsponge is developing as a novel drug delivery system for controlled release of medicinally active ingredients. It is generally prepared by polymerization or quasi emulsion solvent diffusion technique and has been successfully used for targeted drug delivery. Microsponges are preferred over the microspheres owing to their better drug loading capacity. The present article deals with recent advancements in the microspon Read More

In present study, Authors review all aspects of microsphere based novel drug delivery system; including need of natural polymers, different approaches for preparation and recent advancements. Microspheres are a novel drug delivery approach to control release of pharmacologically active ingredient as per patient needs. Natural polymers are cheap, biodegradable and have been proved safe for pharmaceutical form Read More

Self-emulsifying compositions are lipidic drug delivery systems that provide a number of delivery advantages. A variety of excipients are available for designing of these drug delivery systems. These systems can be classified as Type I, II, III, and IV, and alternatively as solid, semi-solid, and liquid. Till date many patents have been published on selfemulsifying compositions, and a few commercial products have also been laun Read More

Pharmaceutical scientists involved in drug discovery and drug development are facing serious problems with newer poorly water soluble drugs with respect to their dissolution and bioavailability. Reducing the particle size of active pharmaceutical ingredient has been an efficient and reliable method for improving the bioavailability of insoluble drugs. Nanosuspension has emerged as an efficient and promising strategy for deliv Read More

Insulin was discovered over 90 years ago. However oral insulin still remains a challenging and elusive goal. Extensive efforts are being made worldwide for developing noninvasive drug delivery systems, mainly via oral route as it is the most widely accepted means of administration. The main barriers faced in oral protein delivery are the enzymatic degradation and poor permeability across the intestinal wall. The approac Read More