- Home
- A-Z Publications
- Current Topics in Medicinal Chemistry
- Previous Issues
- Volume 23, Issue 18, 2023
Current Topics in Medicinal Chemistry - Volume 23, Issue 18, 2023
Volume 23, Issue 18, 2023
-
-
Review of the Application of PAT in the Pharmaceutical Continuous Crystallization Process
Authors: Bing Zhao, Hengchang Zang, Liang Zhong, Xiaobo Ma, Haowei Wang, Hui Zhang and Lian LiAs an important pharmaceutical process, crystallization greatly impacts the final product. In recent years, the continuous crystallization process has attracted more attention from researchers, with the promotion of continuous manufacturing (CM) by the Food and Drug Administration (FDA). The continuous crystallization process has the advantages of high economic benefit, stable and uniform quality, a short production cycle, an Read More
-
-
-
Epigenetics Mechanism and Therapeutic Potential of Approved Epi-drugs in Pulmonary Hypertension Disease
Authors: Li Zhanqiang, Huang Huoqiang and Lu DianxiangEpigenetics is defined as a heritable change occurring in gene expression and phenotype without altering the underlying primary DNA sequence itself. Epigenetic variation consists of DNA methylation repatterning, posttranslational modification of histone proteins, and non-coding RNAs (ncRNAs). Epigenetic modifications are deeply involved in tumorigenesis and tumor development. Epigenetic abnormalities can be thera Read More
-
-
-
Chronic Hepatitis B Infection: Current and Emerging Therapeutic Strategies
Authors: Ankita Singh, Jitendra Kumar and Vijay KumarThe chronic infection of the hepatitis B virus (CHB) represents a major public health problem worldwide. Despite the availability of an effective prophylactic vaccine, millions of hepatitis B patients are at increased risk of developing chronic liver disease. The currently available treatments for HBV infection include interferon and nucleos(t)ide analogues that are effective at suppressing viral load and preventing or delaying the p Read More
-
-
-
Propolis: Antineoplastic Activity, Constituents, and Mechanisms of Action
Propolis is a beehive product with great pharmacological potential, including antineoplastic activity. Objectives: The aim of this study is to provide an actual understanding of the existent scientific information regarding the antiproliferative effect of propolis, proposed mechanisms of action, and challenges to meet. Methods: An assessment of the scientific literature was attained using the PubMed and SciFinder platforms. Researc Read More
-
-
-
Current Medicinal Insights on Synthetic Small Molecules and Natural Origin Products as PD-1/PD-L1 Inhibitors
Authors: Shivanshu Pandey, Balak D. Kurmi and Preeti PatelCancer is one of the leading causes of death worldwide. Each year, millions of people are diagnosed with cancer; hence, researchers have always been curious and busy developing cancer treatments. Despite thousands of studies, cancer is still a major threat to human beings. One of the mechanisms through which cancer invades a human being is the immune escape mechanism, which has been the focus of studies in th Read More
-
-
-
The Gut Microbiota-Brain Axis: Potential Mechanism of Drug Addiction
Authors: Xiao Luo, Hong Li, Xuan Fan, Xiaocong Wu, Ruiyi Zhou, Yi Lei, Dan Xue, Fazheng Yang, Yu Xu and Kunhua WangAs a chronic encephalopathy, drug addiction is responsible for millions of deaths per year around the world. The gut microbiome is a crucial component of the human microbiome. Through dynamic bidirectional communication along the 'gut-brain axis,' gut bacteria cooperate with their hosts to regulate the development and function of the immune, metabolic, and nervous systems. These processes may affect human he Read More
-
Volumes & issues
-
Volume 25 (2025)
-
Volume 24 (2024)
-
Volume 23 (2023)
-
Volume 22 (2022)
-
Volume 21 (2021)
-
Volume 20 (2020)
-
Volume 19 (2019)
-
Volume 18 (2018)
-
Volume 17 (2017)
-
Volume 16 (2016)
-
Volume 15 (2015)
-
Volume 14 (2014)
-
Volume 13 (2013)
-
Volume 12 (2012)
-
Volume 11 (2011)
-
Volume 10 (2010)
-
Volume 9 (2009)
-
Volume 8 (2008)
-
Volume 7 (2007)
-
Volume 6 (2006)
-
Volume 5 (2005)
-
Volume 4 (2004)
-
Volume 3 (2003)
-
Volume 2 (2002)
-
Volume 1 (2001)
Most Read This Month
Article
content/journals/ctmc
Journal
10
5
false
en
