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- Volume 22, Issue 17, 2022
Current Topics in Medicinal Chemistry - Volume 22, Issue 17, 2022
Volume 22, Issue 17, 2022
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Ziziphi Spinosae Semen: A Natural Herb Resource for Treating Neurological Disorders
Authors: Mei Zhang, Jinrui Liu, Yanqing Zhang and Junbo XieNeurological disorders generally have the characteristics of occult onset and progressive development, which can do some serious damage to the human body in the aging process. It is worth noting that traditional medicine can potentially prevent and treat such diseases. Ziziphi Spinosae Semen (ZSS), the seeds of Ziziphus jujuba var. spinosa, has a long clinical history for sleep regulation. In recent years, ZSS has been pro Read More
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Therapeutic Potential of Naturally Occurring Lignans as Anticancer Agents
More LessCancer is a long-term and deadly pandemic that affects nearly a third of the world's population. Chemotherapy is currently the most common therapeutic treatment, but it is difficult to achieve satisfactory efficacy due to drug resistance and adverse effects.Natural products are becoming increasingly popular in cancer therapy due to their potent broad-spectrum anticancer potency and slight side effects. Lignans are compl Read More
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1,2,3-Triazole Derivatives with Anti-breast Cancer Potential
Authors: Xinyi Wu, Jun Wang, Shiqi Xia, Shishuo Cheng and Yumin ShiBreast cancer is one of the most prevalent malignant diseases, and one of the main causes of mortality among women across the world. Despite advances in chemotherapy, drug resistance remains a major clinical concern, creating an urgent need to explore novel anti-breast cancer drugs. 1,2,3-triazole is a privileged moiety, and its derivatives could inhibit cancer cell proliferation and induce cell cycle arrest and apoptosis. A Read More
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Recent Updates on the Anticancer Activity of Quinoxaline Hybrids (Jan. 2017-Jan. 2022)
Authors: Lian-Shun Feng, Chuan Gao, Fa-Wu Liu, Xiao-Ping Wang and Zhi-Liu ZhangCancer being one of the leading causes of death among non-communicable diseases, has already posed a heavy burden on the world health system. Chemotherapy is one of the most effective approaches for cancer treatment, but multidrug resistance, lack of efficacy, and toxic side effects hamper efficacious cancer chemotherapy, creating an urgent need to develop novel, more effective and less toxic anticancer th Read More
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Naturally Occurring Steroidal Saponins as Potential Anticancer Agents: Current Developments and Mechanisms of Action
By Yulin ZouCancer is claimed as a prevalent cause of mortality throughout the world. Conventional chemotherapy plays a pivotal role in the treatment of cancers, but multidrug resistance has already become one of the major impediments to efficacious cancer therapy, creating a great demand for the development of novel anticancer drugs. Steroidal saponins, abundantly found in nature, possess extensive structural variability, and Read More
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Volumes & issues
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Volume 25 (2025)
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Volume 24 (2024)
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Volume 23 (2023)
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Volume 22 (2022)
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Volume 21 (2021)
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Volume 20 (2020)
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Volume 19 (2019)
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Volume 18 (2018)
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Volume 17 (2017)
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Volume 16 (2016)
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Volume 15 (2015)
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Volume 14 (2014)
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Volume 13 (2013)
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Volume 12 (2012)
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Volume 11 (2011)
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Volume 10 (2010)
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Volume 9 (2009)
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Volume 8 (2008)
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Volume 7 (2007)
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Volume 6 (2006)
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Volume 5 (2005)
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Volume 4 (2004)
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Volume 3 (2003)
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Volume 2 (2002)
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Volume 1 (2001)
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