A Review of Pediatric Mediastinal Masses and Castleman's Disease

Pediatric thoracic masses are usually found in the mediastinum. The three anatomic compartments each have distinct differential diagnoses. Castleman's Disease, a rare form of giant lymph node hyperplasia has been described in children with mediastinal masses. While most forms are localized, multicentric disease can also occur. This review provides a summary of pediatric mediastinal disease.