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2000
Volume 28, Issue 9
  • ISSN: 1381-6128
  • E-ISSN: 1873-4286

Abstract

Background: Quercetin is the main dietary flavonoid with a wide range of pharmacological activities. However, the poor gastrointestinal absorption and low bioavailability of quercetin curtail its clinical applications. Methods: We performed a systematic research on the quercetin drug delivery system in PubMed, Web of Science, SciFinder, Google Scholar, Chinese National Knowledge Infrastructure database, and summarized it reasonably. Result and Conclusion: The bioavailability of quercetin can be improved through the application of delivery systems technologies, such as microparticle delivery systems, solid dispersions, encapsulation, phospholipid complexes, and hydrogels. Quercetin delivery systems have been demonstrated to exhibit stronger antibacterial, anti-oxidant, anti-inflammatory, anti-cancer, and other pharmacological effects in vitro and in vivo animal experiments, promoting the development and optimization of quercetin delivery systems for clinical applications.</P>

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/content/journals/cpd/10.2174/1381612828666220317141923
2022-03-01
2025-04-10
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