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Volume 18, Issue 29
  • ISSN: 1381-6128
  • E-ISSN: 1873-4286

Abstract

Immunosuppressive treatment still is an important element in the management of autoimmune mediated diseases. However, immunosuppressive therapy is often complicated by a narrow therapeutic index and high variability of treatment response. This review discusses the clinical management and monitoring strategies for the use of ciclosporin A, tacrolimus, azathioprine, mycophenolat mofetil, mitoxantrone and some monoclonal antibodies with focus on natalizumab.

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/content/journals/cpd/10.2174/138161212802502152
2012-10-01
2025-04-20

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  • Article Type:     Research Article
Keyword(s): azathioprine; ciclosporin A; immunosuppressive therapy; mitoxantrone; monoclonal antibodies; mycophenolat mofetil; natalizumab; Neuroimmunology; tacrolimus; therapeutic drug monitoring

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