Ontologies of Drug Discovery and Design for Neurology, Cardiology and Oncology

Jose M. Vazquez-Naya; Marcos Martinez-Romero; Ana B. Porto-Pazos; Francisco Novoa; Manuel Valladares-Ayerbes; Javier Pereira; Cristian R. Munteanu; Julian Dorado

doi:10.2174/138161210792389199

ISSN: 1381-6128
E-ISSN: 1873-4286

Ontologies of Drug Discovery and Design for Neurology, Cardiology and Oncology
Authors: Jose M. Vazquez-Naya¹, Marcos Martinez-Romero², Ana B. Porto-Pazos³, Francisco Novoa⁴, Manuel Valladares-Ayerbes⁵, Javier Pereira⁶, Cristian R. Munteanu⁷ and Julian Dorado⁸
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Affiliations: ¹ Department of Information and Communication Technologies, Computer Science Faculty, University of A Coruna, Campus de Elvina s/n, 15071 A Coruna, Spain. ² Department of Information and Communication Technologies, Computer Science Faculty, University of A Coruna, Campus de Elvina s/n, 15071 A Coruna, Spain. ³ Department of Information and Communication Technologies, Computer Science Faculty, University of A Coruna, Campus de Elvina s/n, 15071 A Coruna, Spain. ⁴ Department of Information and Communication Technologies, Computer Science Faculty, University of A Coruna, Campus de Elvina s/n, 15071 A Coruna, Spain. ⁵ Department of Information and Communication Technologies, Computer Science Faculty, University of A Coruna, Campus de Elvina s/n, 15071 A Coruna, Spain. ⁶ Department of Information and Communication Technologies, Computer Science Faculty, University of A Coruna, Campus de Elvina s/n, 15071 A Coruna, Spain. ⁷ Department of Information and Communication Technologies, Computer Science Faculty, University of A Coruna, Campus de Elvina s/n, 15071 A Coruna, Spain. ⁸ Department of Information and Communication Technologies, Computer Science Faculty, University of A Coruna, Campus de Elvina s/n, 15071 A Coruna, Spain.
Source: Current Pharmaceutical Design, Volume 16, Issue 24, Aug 2010, p. 2724 - 2736
DOI: https://doi.org/10.2174/138161210792389199
- Available online: 01 Aug 2010

Abstract

The complex diseases in the field of Neurology, Cardiology and Oncology have the most important impact on our society. The theoretical methods are fast and they involve some efficient tools aimed at discovering new active drugs specially designed for these diseases. The ontology of all the items that are linked with the molecule metabolism and the treatment of these diseases gives us the possibility to correlate information from different levels and to discover new relationships between complex diseases such as common drug targets and disease patterns. This review presents the ontologies used to process drug discovery and design in the most common complex diseases.

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2010-08-01

2024-11-14

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Article Type: Research Article

Keyword(s): (ICD-NA); Alzheimer’s disease; complex disease; Drug design; Drug Discovery Investigations ontology (DDI); Drug Interaction Ontology (DIO); EBI; multi-factorial diseases; National Drug Data File (NDDF); NCI Thesaurus (NCI-T); NDF; ontology; Parkinson’s disease; prostaglandin synthases; Protein Modification (PSI-MOD); Protein Ontology (PRO); RxNorm; SNOMED-CT

Ontologies of Drug Discovery and Design for Neurology, Cardiology and Oncology

Abstract

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