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Volume 15, Issue 5
  • ISSN: 1381-6128
  • E-ISSN: 1873-4286

Abstract

Fenofibrate represents the most commonly used fibric acid derivative. The drug exerts its metabolic effects by modulating the expression of several genes involved in lipoprotein metabolism. In addition, numerous studies suggest that fenofibrate may also affect the progression of the atherosclerotic process by several lipid-independent mechanisms. This review considers the clinical pharmacology of fenofibrate and the current evidence on the pleiotropic effects of this fibric acid derivative.

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/content/journals/cpd/10.2174/138161209787315675
2009-02-01
2025-04-16

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  • Article Type:     Research Article
Keyword(s): angiogenesis; cardiac remodeling; endothelial function; Fenofibrate; inflammation; lipoprotein-associated enzymes; oxidative stress; pleiotropic effects

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