The Importance of Growth Hormone (GH) and GH Secretagogues for Bone Mass and Density

Potent antiresorptive agents have been developed for the treatment of osteoporosis and bone disorders. There are few agents available that stimulate bone formation. Recently, treatment with parathyroid hormone was found to induce a potent increase in hip and lumbar bone mineral density (BMD). The present review focus on growth hormone (GH) / growth hormone secretagogues (GHSs). GH / GHSs stimulates bone turnover, thereby increasing bone mass and density.