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2000
Volume 6, Issue 4
  • ISSN: 1381-6128
  • E-ISSN: 1873-4286

Abstract

The phrase molecular target-based drug discovery usually implies an in vitro biochemical assay or battery of assays. One portion of the U.S. National Cancer Institutes drug discovery program, to the contrary, examines molecular targets for cancer therapy in a cell-based format. That approach has a number of sig-nificant limitations, but it has produced databases of significant utility on the activities and structures of tested compounds, as well as on molecular characteristics of the cell types used for testing.

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/content/journals/cpd/10.2174/1381612003400894
2000-03-01
2024-11-01
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