Stem Cell Nanotechnology Applications as Drug Delivery Systems for Neurodegenerative Disorders

References

1. Samuel P. Sundarraj S. Sudarmani D. Nanotechnology-based stem cell therapy: Current status and perspectives. Possibilities and limitations in current translational stem cell research. London, UK IntechOpen 2023 109275 10.5772/intechopen.109275
   [Google Scholar]
2. Rao M. Khanna A. Shin S. Shin S. Stem cells for the treatment of neurological disorders. CNS Neurol. Disord. Drug Targets 2008 7 1 98 109 10.2174/187152708783885183 18289036
   [Google Scholar]
3. Lindvall O. Kokaia Z. Stem cells for the treatment of neurological disorders. Nature 2006 441 7097 1094 1096 10.1038/nature04960 16810245
   [Google Scholar]
4. Labusca L. Herea D.D. Mashayekhi K. Stem cells as delivery vehicles for regenerative medicine-challenges and perspectives. World J. Stem Cells 2018 10 5 43 56 10.4252/wjsc.v10.i5.43 29849930
   [Google Scholar]
5. Ahad Mir P.R.I.N.C.E. Hussain M.S. Ahmad Khanday M. Mohi-ud-din R. Pottoo F.H. Hasssan Mir R. Immunomodulatory roles of mesenchymal stem cell-derived extracellular vesicles: A promising therapeutic approach for autoimmune diseases. Curr. Stem Cell Res. Ther. 2024 20 1 4 10.2174/011574888X341781241216044130 39757602
   [Google Scholar]
6. Francois S. Mouiseddine M. Allenet-Lepage B. Voswinkel J. Douay L. Benderitter M. Chapel A. Human mesenchymal stem cells provide protection against radiation-induced liver injury by antioxidative process, vasculature protection, hepatocyte differentiation, and trophic effects. BioMed Res. Int. 2013 2013 1 14 10.1155/2013/151679 24369528
   [Google Scholar]
7. Jin Y. Li S. Yu Q. Chen T. Liu D. Application of stem cells in regeneration medicine. Med. Comm. 2023 4 4 e291 10.1002/mco2.291 37337579
   [Google Scholar]
8. Wu H.H. Zhou Y. Tabata Y. Gao J.-Q. Mesenchymal stem cell-based drug delivery strategy: From cells to biomimetic. J. Cont. Rel. 2019 294 102 113 10.1016/j.jconrel.2018.12.019 30553849
   [Google Scholar]
9. Sadique Hussain M. Gupta G. Ghaboura N. Moglad E. Almalki W.H. Alzarea S.I. Exosomal ncRNAs in liquid biopsies for lung cancer. Clin. Chim. Acta. 2025 565 119983 10.1016/j.cca.2024.119983 39368685
   [Google Scholar]
10. Rezaie J. Nejati V. Mahmoodi M. Ahmadi M. Mesenchymal stem cells derived extracellular vesicles: A promising nanomedicine for drug delivery system. Biochem. Pharmacol. 2022 203 115167 10.1016/j.bcp.2022.115167 35820499
    [Google Scholar]
11. Fan L. Wei A. Gao Z. Mu X. Current progress of mesenchymal stem cell membrane-camouflaged nanoparticles for targeted therapy. Biomed. Pharmacoth. 2023 161 114451 10.1016/j.biopha.2023.114451 36870279
    [Google Scholar]
12. Lee E.J. Choi Y. Lee H.J. Hwang D.W. Lee D.S. Human neural stem cell-derived extracellular vesicles protect against Parkinson’s disease pathologies. J. Nanobiotechnology 2022 20 1 198 10.1186/s12951‑022‑01356‑2 35468855
    [Google Scholar]
13. Jafarinia M. Alsahebfosoul F. Salehi H. Eskandari N. Azimzadeh M. Mahmoodi M. Asgary S. Ganjalikhani Hakemi M. Therapeutic effects of extracellular vesicles from human adipose‐derived mesenchymal stem cells on chronic experimental autoimmune encephalomyelitis. J. Cell. Physiol. 2020 235 11 8779 8790 10.1002/jcp.29721 32329062
    [Google Scholar]
14. Chung T.H. Hsu S.C. Wu S.H. Hsiao J.K. Lin C.P. Yao M. Huang D.M. Dextran-coated iron oxide nanoparticle-improved therapeutic effects of human mesenchymal stem cells in a mouse model of Parkinson’s disease. Nanoscale 2018 10 6 2998 3007 10.1039/C7NR06976F 29372743
    [Google Scholar]
15. Riazifar M. Mohammadi M.R. Pone E.J. Yeri A. Lässer C. Segaliny A.I. McIntyre L.L. Shelke G.V. Hutchins E. Hamamoto A. Calle E.N. Crescitelli R. Liao W. Pham V. Yin Y. Jayaraman J. Lakey J.R.T. Walsh C.M. Van Keuren-Jensen K. Lotvall J. Zhao W. Stem cell-derived exosomes as nanotherapeutics for autoimmune and neurodegenerative disorders. ACS Nano 2019 13 6 6670 6688 10.1021/acsnano.9b01004 31117376
    [Google Scholar]
16. Marei H.E. Elnegiry A.A. Zaghloul A. Althani A. Afifi N. Abd-Elmaksoud A. Farag A. Lashen S. Rezk S. Shouman Z. Cenciarelli C. Hasan A. Nanotubes impregnated human olfactory bulb neural stem cells promote neuronal differentiation in Trimethyltin‐induced neurodegeneration rat model. J. Cell. Physiol. 2017 232 12 3586 3597 10.1002/jcp.25826 28121007
    [Google Scholar]
17. Ren H. Li J. Peng A. Liu T. Chen M. Li H. Wang X. Water-soluble, alanine-modified fullerene c(60) promotes the proliferation and neuronal differentiation of neural stem cells. Int. J. Mol. Sci. 2022 23 10 5714 10.3390/ijms23105714 35628525
    [Google Scholar]
18. Fu H. Wu Y. Yang X. Huang S. Yu F. Deng H. Zhang S. Xiang Q. Stem cell and its derivatives as drug delivery vehicles: An effective new strategy of drug delivery system. All Life 2021 14 1 782 798 10.1080/26895293.2021.1967202
    [Google Scholar]
19. Mojsilović S. Jauković A. Kukolj T. Obradović H. Okić Đorđević I. Petrović A. Bugarski D. Tumorigenic aspects of msc senescence-implication in cancer development and therapy. J. Pers. Med. 2021 11 11 1133 10.3390/jpm11111133 34834485
    [Google Scholar]
20. Kazmi I. Yadav H.K.S. Al-Abbasi F.A. Afzal M. Nadeem M.S. Altayb H.N. Raizaday A. Hussain M.S. Ali H. Imam F. Gupta G. Design of in-situ implant for the brain-targeted drug delivery using cross-linked gellan gum polymer through response surface methodology. Ann. Pharm. Fr. 2025 83 1 68 80 10.1016/j.pharma.2024.10.004 39419475
    [Google Scholar]
21. Hermerén G. Ethical challenges for using human cells in clinical cell therapy. Prog. Brain Res. 2012 200 17 40 10.1016/B978‑0‑444‑59575‑1.00002‑8 23195413
    [Google Scholar]