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A Comprehensive Pan-Cancer Analysis Identified that TRIB3 was Associated with Immune Cell Infiltration and Poor Prognosis
Authors: Ke-Xun Yu, Wei-Jie Yuan, Jing-Li, Hui-Zhen Wang and Yong-Xiang LiAvailable online: 12 September 2024More LessBackground Previous studies have demonstrated that TRIB3 plays a carcinogenic role in tumor progression. However, the exploration of TRIB3 at the pan-cancer level has not been reported. Aims This study aimed to conduct a comprehensive pan-cancer analysis of TRIB3. Objective We explored the expression pattern and functional mechanism of TRIB3 on the basis of multiple databases. Method We first explored the ex Read More
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cRGD-platelet@MnO/MSN@PPARα/LXRα Nanoparticles Improve Atherosclerosis in Rats by Inhibiting Inflammation and Reducing Blood Lipid
Authors: Zheng Lv, Yupeng Zhang, Mengke Lu, Ziyi Wang, Xiaoyue Nong, Guoliang Wen and Wei ZhangAvailable online: 02 September 2024More LessObjective Atherosclerosis (AS) is an inflammatory disease of arterial intima driven by lipids. Liver X receptor alpha (LXRα) and peroxisome proliferator-activated receptor alpha (PPARα) agonists are limited in the treatment of AS due to their off-target effects and serious side effects. Therefore, this study was designed to construct a novel nanoparticle (NP) and evaluate its mechanism of action on inflammation inhibiti Read More
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