Skip to content
2000
Volume 15, Issue 5
  • ISSN: 1389-2010
  • E-ISSN: 1873-4316

Abstract

MiRNAs are a family of small, endogenous, and evolutionarily conserved non-coding ribonucleic acids that have been involved in the regulation of several essential, cellular, and functional processes. MicroRNAs are known to play key roles in all types of cancer and function as oncogenes (oncomirs) or tumour-suppressors in up-regulation or down-regulation processes respectively. MiRNAs have potential power to be examined as prognostic and diagnostic biomarkers. Modulating miRNAs, based on two major approaches (miRNA mimics and miRNA antagonists), is used for clinical development of therapeutic miRNAs. This review emphasizes the latest discovery in the field of miRNA research involved in cancer, biomarkers, and therapeutics.

Loading

Article metrics loading...

/content/journals/cpb/10.2174/1389201015666140519095304
2014-05-01
2025-07-06
Loading full text...

Full text loading...

/content/journals/cpb/10.2174/1389201015666140519095304
Loading

  • Article Type:
    Research Article
Keyword(s): Biomarkers; cancer; microRNAs; therapeutics
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test