Recent Developed Nitrogen/Sulfur Heterocyclic Compounds with Marked and Selective Antiviral Activities (Microreview)

Millions of deaths have been reported due to viral infections in medical history, and various viral infections are mentioned as the main cause of death. Although different types of research have been conducted to develop effective medication, there is a high demand to truly cure various viral infections. The resistance to the existence of antiviral drugs on the market is the main threat to human health, and an intrinsic demand to develop and synthesize new scaffolds is highly required to find less toxicity and high antiviral activity. Nitrogen-sulfur heterocyclic compounds have extensively exhibited efficient biological and pharmacological activity against viral species, and physicochemical and pharmacokinetic properties. In this microreview, recently developed nitrogen-sulfur heterocyclics and their performance with marked and selective antiviral activities are summarized. We hope this micro-review will help early scientists interested in the design of new compounds with selective and pronounced antiviral activities to identify and satisfy the necessary criteria for the further development of nitrogen-sulfur heterocyclic compounds.