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- ISSN: 1385-2728
- E-ISSN: 1875-5348
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Ytterbium Triflate: A Versatile Catalyst in Organic Synthesis
- Source: Current Organic Chemistry, Volume 17, Issue 23, Dec 2013, p. 2906 - 2920
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- 01 Dec 2013
Abstract
Ytterbium triflate, Yb(OTf)3, is a versatile Lewis acid that has high catalytic activity in many organic reactions, including aldol, Michael, Mannich, Friedel-Crafts, Diels-Alder, and some other types of reactions. Less than 10 mol% of Yb(OTf)3 is normally sufficient for most organic transformations and can be recovered and re-used without loss of catalytic activity. In addition, Yb(OTf)3 is very stable and its catalyzed reactions can be carried out in both organic solvents and aqueous conditions.
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