Binaphthyl-Derived Mono-, Bi- and Multi-Functional Lewis and Brønsted Base Organocatalysts: A New Vista for Asymmetric Synthesis

Lewis and Bronsted base catalysis are rapidly growing areas in organocatalysis. Numerous binaphthyl-derived chiral base catalysts has been developed over the last years. Recent progress in the chiral Lewis and Bronsted base catalysis has been reviewed with a focus being placed on mono-functional catalysts, including primary and secondary diamines, guanidines, phosphines and phosphineoxides; bi- and multifunctional catalysts, covering secondary and/or tertiary amine and phosphine derivatives assisted with urea/thiourea hydrogen bond donors or Lewis/ Bronsted acids.