Synthesis and Reactions of Pyrazolo[1,5-a]pyridines and Related Heterocycles

Pyrazolo[1,5-a]pyridines have become subject to growing interest by both synthetic and medicinal chemists, and as such new and simple methods for their synthesis are becoming increasingly more important. They exhibit reactivity which permits substitution at various positions, allowing many diverse chemical structures to be made. This review briefly discusses the medicinal uses of pyrazolo[1,5-a]pyridines, it outlines the synthetic methods which have been used to make them and discusses the chemistries which have been carried out to further functionalise the ring system.