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The present review covers the topic of microwave-assisted reduction of organic compounds including catalytic (metalcatalyzed hydrogenation, catalytic transfer hydrogenation) and stochiometric reactions (ionic and transfer hydrogenation). The article is subcategorized with respect to the different functionalities which so far have been subjected to reduction: C-C multiple bonds, carbonyls, N-containing functional groups, aromatics and heteroaromatics, reductive deprotection strategies, and miscellaneous reactions like dehalogenation or hydrogen-deuterium exchange.