Skip to content
2000
  1. Home
  2. A-Z Publications
  3. Current Organic Chemistry
  4. Volume 14, Issue 17
  5. Article
Volume 14, Issue 17
  • ISSN: 1385-2728
  • E-ISSN: 1875-5348

Abstract

Naturally occurring enzymes are truly remarkable catalysts. However, many are not suitable for practical synthetic chemistry because of poor substrate or product selectivity. This review highlights recent advances in engineering enzymes for selective catalysis. Selected topics include altering substrate specificity, altering substrate and product selectivity, engineering enzymes that catalyze carboncarbon bond formation or carbon-oxygen bond cleavage and formation, and engineering multi-function enzymes such as polyketide synthases.

© Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/coc/10.2174/138527210792927537
2010-10-01
2025-05-19

  • From This Site

    /content/journals/coc/10.2174/138527210792927537
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

/content/journals/coc/10.2174/138527210792927537
Loading

  • Article Type:     Research Article
Keyword(s): (C-C) bond formation; (FMN); (NAL); (PTDH); (TAL); (UNGPase); B.megaterium; Bacillus megaterium; BFD; biocatalysis; biocatalysts; C3-C8; Candida boidinii; CASTing; creatine kinase; cytochrome P450 2B1; Cytochrome P450 monooxygenases; DERA; Directed evolution; DNA shuffling; E.coli; enantioselectivity; enzyme engineering; Enzymes; epPCR; FACS; FAD; FDA; FDH; GeneReassembly; glycocyamine kinases; Glycosidases; HPLC; hydantoinase; L-enantiomer; L-methionine; Lipitor; MAO-N; NADH; NADPH; polyketide synthases; Polyketides; Pseudomonas aeruginosa; Pseudomonas putida; Pseudomonas stutzeri; regioselectivity; selectivity; StEP; TSSM; Type I PKSs; Type II PKSs; Type III PKSs; UGPase; UTP; XR

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test