Synthesis, Photophysical and Photobiological Study of Synergic Photosensitizer:Zinc-Phthalocyanine with Ca2+ Chelating Agent

Claure N. Lunardi; Jeane C. G. Rotta; Antonio C. Tedesco

doi:10.2174/138527207780598792

ISSN: 1385-2728
E-ISSN: 1875-5348

Synthesis, Photophysical and Photobiological Study of Synergic Photosensitizer:Zinc-Phthalocyanine with Ca2+ Chelating Agent
Authors: Claure N. Lunardi¹, Jeane C. G. Rotta² and Antonio C. Tedesco³
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¹ Departamento de Quimica,FFCLRP, Universidade de Sao Paulo, Av. dos Bandeirantes, 3900, 14040-901, Ribeirao Preto, SP, Brasil. ² Departamento de Quimica,FFCLRP, Universidade de Sao Paulo, Av. dos Bandeirantes, 3900, 14040-901, Ribeirao Preto, SP, Brasil. ³ Departamento de Quimica,FFCLRP, Universidade de Sao Paulo, Av. dos Bandeirantes, 3900, 14040-901, Ribeirao Preto, SP, Brasil.
Source: Current Organic Chemistry, Volume 11, Issue 7, May 2007, p. 647 - 654
DOI: https://doi.org/10.2174/138527207780598792
- Available online: 01 May 2007

Abstract

A novel phthalocyanine derivative containing a Ca2+ chelating agent with structure similar to EDTA has been synthesized in 3 steps. The addition of a chelating agent to the phthalocyanine macrocycle make it a synergic compound useful for PDT.

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2007-05-01

2025-05-18

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Article Type: Research Article

Keyword(s): Calcium affinity; fluorescence emission; MTT Assay; Photoinactivation; ZnPcChel

Synthesis, Photophysical and Photobiological Study of Synergic Photosensitizer:Zinc-Phthalocyanine with Ca2+ Chelating Agent

Abstract

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