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This issue of Current Organic Chemistry constitutes the second part of a whole body of work dedicated to RECENT ADVANCES IN SELECTIVE BIOCATALYSIS. In Part II enzymatic activity related to nucleoside phosphorylases will be discussed (A. Iribarren). Biocatalytic reduction of carbonyl compounds (K. Nakamura), oxidations mediated by isolated or cellbound dehydrogenases/oxidases (F. Molinari) as will as enzyme-catalyzed Baeyer-Villiger processes (M. D. Mihovilovic) will be also presented. Finally, the biocatalytic approach to the synthesis of chiral intermediates for pharmaceuticals will be reviewed (R. N. Patel). A warm thank to renowned experts in the field that have accepted to contribute to Part I and Part II is deeply expressed. Their commitment is highly appreciated as an expression of competence and profound involvment in biocatalysis. All authors hope that the whole work will offer a useful contribution to biocatalysis, a well established field of investigation still open to new challenges and fascinating discoveries.