Full text loading...
- ISSN: 1385-2728
- E-ISSN: 1875-5348
-
Asymmetric Ring Opening of Epoxides
- Source: Current Organic Chemistry, Volume 9, Issue 1, Jan 2005, p. 1 - 29
-
- 01 Jan 2005
- Previous Article
- Table of Contents
- Next Article
Abstract
This review deals with the metal promoted asymmetric ring opening of achiral epoxides using achiral carbon-, nitrogen-, oxygen-, sulphur- and halogen-containing nucleophiles. The use of chiral bases in the asymmetric deprotonation of achiral epoxides yields chiral allylic alcohols. Finally, kinetic resolution of racemic epoxides can be achieved using chiral metal complexes.
© Bentham Science Publishers