Skip to content
2000
  1. Home
  2. A-Z Publications
  3. Current Neurovascular Research
  4. Volume 21, Issue 5
  5. Article
Volume 21, Issue 5
  • ISSN: 1567-2026
  • E-ISSN: 1875-5739

Abstract

Objective

We aimed to investigate the prognostic factors associated with lobar intracerebral hemorrhage (ICH) and to construct convenient models to predict 3-month unfavorable functional outcomes or all-cause death.

Methods

Our study included 322 patients with spontaneous lobar ICH from 13 hospitals in Beijing as a derivation cohort. The clinical outcomes were unfavorable functional prognosis, defined as a modified Rankin Scale (mRS) score of 4-6, or all-cause death. Variable selection was performed using the Least Absolute Shrinkage and Selection Operator (LASSO) analysis, and two nomogram models were constructed. Additionally, multivariable logistic regression analysis was conducted to identify the factors associated with unfavorable prognosis. Finally, the Area Under The Receiver Operating Characteristic Curve (AUROC), calibration curve, and decision curve analyses (DCA) were performed to evaluate the models in both the derivation and external validation cohorts.

Results

Predictive factors for unfavorable functional outcomes in lobar ICH included age, dyslipidemia, ICH volume, NIHSS score, Stroke-Associated Pneumonia (SAP), and lipid-lowering therapy. The model included age, GCS score, NIHSS score, antihypertensive therapy, in-hospital rehabilitation training, and ICH volume to predict all-cause mortality. Our models exhibited good discriminative ability, with an AUC of 0.897 (95% CI: 0.862-0.933) for unfavorable functional outcomes and 0.894 (95% CI: 0.870-0.918) for death. DCA and calibration curves confirmed the models' excellent clinical decision-making and calibration capabilities.

Conclusion

Nomogram models for predicting 3-month unfavorable outcomes or death in patients with lobar ICH were developed and independently validated in this study, providing valuable prognostic information for clinical decision-making.

© 2024 Bentham Science Publishers
Loading

Article metrics loading...

/content/journals/cnr/10.2174/0115672026365579241220073506
2024-12-26
2025-04-05

  • From This Site

    /content/journals/cnr/10.2174/0115672026365579241220073506
    dcterms_title,dcterms_subject,pub_keyword
    -contentType:Contributor -contentType:Concept -contentType:Institution
    10
    5
Loading full text...

Full text loading...

References

  1. ShethK.N. Spontaneous intracerebral hemorrhage.N. Engl. J. Med.2022387171589159610.1056/NEJMra220144936300975
     [Google Scholar]
  2. KittnerS.J. SekarP. ComeauM.E. AndersonC.D. ParikhG.Y. TavarezT. FlahertyM.L. TestaiF.D. FrankelM.R. JamesM.L. SungG. ElkindM.S.V. WorrallB.B. KidwellC.S. GonzalesN.R. KochS. HallC.E. BirnbaumL. MaysonD. CoullB. MalkoffM.D. ShethK.N. McCauleyJ.L. OsborneJ. MorganM. GilkersonL.A. BehymerT.P. DemelS.L. MoomawC.J. RosandJ. LangefeldC.D. WooD. Ethnic and racial variation in intracerebral hemorrhage risk factors and risk factor burden.JAMA Netw. Open202148e212192110.1001/jamanetworkopen.2021.2192134424302
     [Google Scholar]
  3. ShahV.A. ThompsonR.E. YenokyanG. AcostaJ.N. AvadhaniR. DlugashR. McBeeN. LiY. HansenB.M. UllmanN. FalconeG. AwadI.A. HanleyD.F. ZiaiW.C. One-year outcome trajectories and factors associated with functional recovery among survivors of intracerebral and intraventricular hemorrhage with initial severe disability.JAMA Neurol.202279985686810.1001/jamaneurol.2022.199135877105
     [Google Scholar]
  4. HemphillJ.C.III BonovichD.C. BesmertisL. ManleyG.T. JohnstonS.C. The ICH score.Stroke200132489189710.1161/01.STR.32.4.89111283388
     [Google Scholar]
  5. GodoyD.A. PiñeroG. Di NapoliM. Predicting mortality in spontaneous intracerebral hemorrhage: Can modification to original score improve the prediction?Stroke20063741038104410.1161/01.STR.0000206441.79646.4916514104
     [Google Scholar]
  6. Ruiz-SandovalJ.L. ChiqueteE. Romero-VargasS. Padilla-MartínezJ.J. González-CornejoS. Grading scale for prediction of outcome in primary intracerebral hemorrhages.Stroke20073851641164410.1161/STROKEAHA.106.47822217379820
     [Google Scholar]
  7. JiR. ShenH. PanY. WangP. LiuG. WangY. LiH. ZhaoX. WangY. China National Stroke Registry (CNSR) investigators A novel risk score to predict 1-year functional outcome after intracerebral hemorrhage and comparison with existing scores.Crit. Care2013176R27510.1186/cc1313024289116
     [Google Scholar]
  8. EslamiV. Tahsili-FahadanP. Rivera-LaraL. GandhiD. AliH. Parry-JonesA. NelsonL.S. ThompsonR.E. Nekoobakht-TakS. DlugashR. McBeeN. AwadI. HanleyD.F. ZiaiW.C. Influence of intracerebral hemorrhage location on outcomes in patients with severe intraventricular hemorrhage.Stroke20195071688169510.1161/STROKEAHA.118.02418731177984
     [Google Scholar]
  9. DelcourtC. SatoS. ZhangS. SandsetE.C. ZhengD. ChenX. HackettM.L. ArimaH. HataJ. HeeleyE. SalmanR.A-S. RobinsonT. DaviesL. LavadosP.M. LindleyR.I. StapfC. ChalmersJ. AndersonC.S. AndersonC.S. ChalmersJ. ArimaH. DavisS. HeeleyE. HuangY. LavadosP. NealB. ParsonsM.W. LindleyR. MorgensternL. RobinsonT. StapfC. TzourioC. WangJ.G. HuangY. ChenS. ChenX.Y. CuiL. LiuZ. LuC. WangJ. WuS. XuE. YangQ. ZhangC. ZhangJ. BeerR. SchmutzhardE. RedondoP. KasteM. SoinneL. TatlisumakT. StapfC. WartenbergK. RicciS. KlijnK. AzevedoE. ChamorroA. ArnoldM. FischerU. KaulS. PandianJ. BoyiniH. SinghS. RabinsteinA.A. EstolC. SilvaG. LavadosP. OlavarriaV.V. RobinsonT.G. SimesR.J. BousserM-G. HankeyG. JamrozikK. JohnstonS.C. LiS. HeeleyE. AndersonC.S. BaileyK. ChalmersJ. CheungT. DelcourtC. ChintapatlaS. DucasseE. ErhoT. HataJ. HolderB. KnightE. LindleyR. LerouxM. SasséT. OdgersE. WalshR. WolfowiczZ. AndersonC.S. ChenG. DelcourtC. FuentesS. LindleyR. PengB. SchnebleH-M. WangM-X. ArimaH. BillotL. HeritierS. LiQ. WoodwardM. DelcourtC. AbimbolaS. AndersonS. ChanE. ChengG. ChmielnikP. HataJ. LeightonS. LiuJ-Y. RasmussenB. SaxenaA. TripathyS. ArmenisM. BaigM.A. NaiduB. StarzecG. SteleyS. AndersonC.S. HeeleyE. LerouxM. DelcourtC. SasséT. KnightE. BaileyK. CheungT. OdgersE. DucasseE. HolderB. WolfowiczZ. WalshR. ChintapatlaS. ErhoT. EstolC. MolesA. RuizA. ZimmermannM. MarinhoJ. AlvesS. AngelimR. AraujoJ. KawakamiL. LavadosP. OlavarriaV.V. BustosC. GonzalezF. MunozP. HuangY. ChenX. HuangY. JiaR. LiN. QuS. ShuY. SongA. SunJ. XiaoJ. ZhaoY. WangJ.G. HuangQ. StapfC. VicautE. ChamamA. ViaudM-C. DertC. FiedlerU. JovisV. KablaS. MarchandS. PenaA. RochaudV. MallikarjunaK. BoyiniH. HasanN. BergeE. SandsetE.C. ForårsveenA.S. RobinsonT. RichardsonD. KumarT. LewinS. PoulterN. FieldJ. AnjumA. WilsonA. PerelmuterH. AgarieA.M. BarbozaA.G. RecchiaL.A. MirandaI.F. RauekS.G. DuplessisR.J. DeweyH. WalkerL. PetroloS. BladinC. SturmJ. CrimminsD. GriffithsD. SchutzA. ZentenoV. ParsonsM.W. MiteffF. SprattN. KerrE. LeviC.R. PhanT.G. MaH. SandersL. MoranC. WongK. ReadS. HendersonR. WongA. HullR. SkinnerG. DavisS. HandP. YanB. TuH. CampbellB. AndersonC.S. DelcourtC. BlackerD.J. WijeratneT. PathirageM. JasinararchchiM. MatkovicZ. CelestinoS. GruberF. VoskoM.R. DiablE. RathmaierS. BeerR. SchmutzhardE. PfauslerB. HelbokR. FazekasF. FischerR. PoltrumB. ZechnerB. TrummerU. RutgersM.P. PeetersA. DusartA. DurayM-C. ParmentierC. Ferrao-SantosS. BrounsR. De RaedtS. De SmedtA. VanHooffR-J. De KeyserJ. MartinsS.C.O. de AlmeidaA.G. BroudaniR. TittonN.F. de FreitasG.R. CardosoF.M. GieselL.M. JuniorN.A.L. Ferraz de AlmeidaA.C. GomesR.B. Borges dos SantosT.S. SoaresE.M.V. NetoO.L.A. SilvaG.S. GomesD.L. de CarvalhoF.A. MirandaM. MarquesA. ZétolaV.F. de MatiaG. LangeM.C. MontesJ. RecciusA. VenturelliP.M. OlavarriaV.V. SotoA. RivasR. KlappC. IllanesS. AguileraC. CastroA. FigueroaC. BenavidesJ. SalamancaP. ConchaM.C. PajaritoJ. ArayaP. GuerraF. LiY. LiuG. WangB. ZhangJ. ChongY. HeM. WangL. LiuJ. ZhangX. LaiC. JiangH. YangQ. CuiS. TaoQ. ZhangY. YaoS. XuM. ZhangY. LiuZ. XiaoH. HuJ. TangJ. SunJ. JiH. JiangM. YuF. ZhangY. YangX. GuoX. WangY. WuL. LiuZ. GaoY. SunD. HuangX. WangY. LiuL. LiY. LiP. JiangY. LiH. LuH. ZhouJ. YuanC. QiX. QiuF. QianH. WangW. LiuJ. HuangY. SunW. LiF. LiuR. PengQ. RenZ. FanC. ZhangY. WangH. WangT. ShiF. DuanC. ChenS. WangJ. ChenZ. TanX. ZhaoZ. GaoY. ChenJ. HanT. WuS. ZhangL. WangL. HuQ. HouQ. ZhaoX. WangL. ZengG. MaL. WangF. ChenS. ZengL. GuoZ. FuY. SongY. TaiL. LiuX. SuX. YangY. DongR. XuY. TianS. ChengS. SuL. XieX. XuT. GengD. YanX. FanH. ZhaoN. WangS. YangJ. ZhangJ. YanM. LiL. LiZ. XuX. WangF. WuL. GuoX. LianY. SunH. LiuD. WangN. TangQ. HanZ. FengL. CuiY. TianJ. ChangH. SunX. WangJ. LiuC. WenZ. XuE. LinQ. ZhangX. SunL. HuB. ZouM. BaoQ. LinX. ZhaoL. TianX. WangH. WangX. LiX. HaoL. DuanY. WangR. WeiZ. LiuJ. RenS. RenH. WangY. DongY. ChengY. ZouM. LiuW. HanJ. ZhangC. ZhangZ. ZhuJ. WangY. LiQ. QianJ. SunY. LiuK. LongF. PengX. ZhangQ. YuanZ. WangC. HuangM. ZhangJ. WangF. HeP. YouY. WangX. YangQ. WangH. XiaJ. ZhouL. HouY. WangY. LiuL. QiY. MeiL. LuR. ChenG. LiuL. PingL. LiuW. ZhouS. WangJ. WangL. LiH. ZhangS. WangL. ZouR. GuoJ. LiM. WeiW. SoinneL. CurtzeS. SaarelaM. StrbianD. ScheperjansF. De BrouckerT. HenryC. CumurciucR. Ibos-AugéN. ZéghoudiA-C. PicoF. DereeperO. SimianM-C. BoisselierC. MahfoudA. TimsitS. MerrienF.M. GuillonB. SevinM. HerissonF. MagneC. AmeriA. CretC. StefanizziS. KlapzcynskiF. DenierC. Sarov-RiviereM. StapfC. ReinerP. MawetJ. HervéD. BuffonF. TouzéE. DomigoV. LamyC. CalvetD. PasquiniM. AlamowitchS. FavroleP. MuresanI-P. CrozierS. RossoC. PiresC. LegerA. DeltourS. CordonnierC. HenonH. RossiC. ZuberM. BruandetM. TamazyanR. Join-LambertC. JuettlerE. KrauseT. MaulS. EndresM. JungehulsingG.J. HennericiM. GriebeM. SauerT. KnollK. HuberR. KnauerK. KnauerC. RauboldS. SchneiderH. HentschelH. LautenschlägerC. SchimmelE. DzialowskiI. FoerchC. LorenzM. SingerO. Meyer dos SantosI.M.R. HartmannA. HamannA. SchachtA. SchraderB. TeíchmannA. WartenbergK.E. MuellerT.J. JanderS. GliemM. BoettcherC. RosenkranzM. BeckC. OttoD. ThomallaG. ChengB. WongK.S. LeungT.W. SooY.O.Y. PrabhakarS. KesavarapuS.R. GajjelaP.K. ChennaR.R. UmmerK. BasheerM. AndipetA. JagarlapudiM.K.M. MohammedA.U.R. PawarV.G. ErankiS.S.K. PandianJ. SinghY. AkhtarN. BorahN.C. GhoseM. ChoudhuryN. IchaporiaN.R. ShendgeJ. KheseS. PamidimukkalaV. InbamuthaiahP. NuthakkiS.R. TagallamudiN.M.R. GuttiA.K. KhuranaD. KesavarapuP. JogiV. GargA. SamantaD. SarmaG.R.K. NadigR. MathewT. AnandanM.A. CaterbiE. ZiniA. CavazzutiM. CasoniF. PentoreR. FalzoneF. RicciS. MazzoliT. GrecoL.M. MenichettiC. CoppolaF. CenciarelliS. GallinellaE. MattioniA. CondursoR. SiciliaI. ZampoliniM. CoreaF. BarbiM. ProiettiC. ToniD. PieroniA. AnziniA. FalcouA. DemicheleM. KlijnC.J.M. TveitenA. ThortveitE.T. PettersenS. HolandN. HitlandB. JohnsenS.H. EltoftA. WasayM. KamalA. IqrarA. AliL. BegumD. GamaG. AzevedoE. FonsecaL. MoreiraG. VelosoL.M. PinheiroD. ParedesL. RozeiraC. GregorioT. MartinT.S. AyoO. Garcia-GarciaJ. VilarI.F. FernándezI.G. ChamorroA. AmaroS. UrraX. ObachV. CerveraA. TruetaJ. SilvaY. SerenaJ. CastellanosM. TercenoM. Van EendenburgC. FischerU. ArnoldM. WeckA. FindlingO. LüdiR. WarburtonE.A. DayD. ButlerN. BumanlagE. CaineS. SteeleA. OsbornM. DoddE. MurphyP. EsisiB. BrownE. HaymanR. BaligaV.K.V. MinphoneM. KennedyJ. RecklessI. PopeG. TealR. MichaelK. ManawaduD. KalraL. LewisR. MistryB. CattermoleE. HassanA. MandizvidzaL. BamfordJ. BrooksH. BedfordC. WhitingR. BainesP. HussainM. HarveyM. FotherbyK. McBrideS. BourkeP. MorganD. Jennings-PreeceK. PriceC. HuntleyS. RiddellV.E. StoreyG. LakeyR.L. SubramanianG. JenkinsonD. KwanJ. DavidO. TiwariD. JamesM. KeenanS. EastwoodH. ShawL. KayeP. ButtonD. MadiganB. WilliamsonD. DixitA. DavisJ. HossainM.O. FordG.A. Parry-JonesA. O’LoughlinV. JarapaR. NaingZ. LovelockC. O’ReillyJ. KhanU. BhallaA. RuddA. BirnsJ. WerringD.J. LawR. PerryR. JonesI. ErandeR. RoffeC. NatarajanI. AhmadN. FinneyK. LucasJ. MistriA. EvesonD. MarshR. HauntonV. RobinsonT. RabinsteinA.A. FugateJ.E. LeporeS.W. INTERACT2 Investigators Intracerebral hemorrhage location and outcome among INTERACT2 participants.Neurology201788151408141410.1212/WNL.000000000000377128235817
     [Google Scholar]
  10. SchragM. KirshnerH. Management of intracerebral hemorrhage.J. Am. Coll. Cardiol.202075151819183110.1016/j.jacc.2019.10.06632299594
     [Google Scholar]
  11. SeiffgeD.J. PolymerisA.A. LawZ.K. KrishnanK. ZietzA. ThilemannS. WerringD. Al-Shahi SalmanR. DineenR.A. EngelterS.T. BathP.M. SpriggN. LyrerP. PetersN. TICH-2 Investigators Cerebral amyloid angiopathy and the risk of hematoma expansion.Ann. Neurol.202292692193010.1002/ana.2648136054211
     [Google Scholar]
  12. MoullaaliT.J. WangX. MartinR.H. ShipesV.B. RobinsonT.G. ChalmersJ. SuarezJ.I. QureshiA.I. PaleschY.Y. AndersonC.S. Blood pressure control and clinical outcomes in acute intracerebral haemorrhage: A preplanned pooled analysis of individual participant data.Lancet Neurol.201918985786410.1016/S1474‑4422(19)30196‑631397290
     [Google Scholar]
  13. DowlatshahiD. DemchukA.M. FlahertyM.L. AliM. LydenP.L. SmithE.E. VISTA Collaboration Defining hematoma expansion in intracerebral hemorrhage.Neurology201176141238124410.1212/WNL.0b013e318214331721346218
     [Google Scholar]
  14. XiG. KeepR.F. HoffJ.T. Mechanisms of brain injury after intracerebral haemorrhage.Lancet Neurol.200651536310.1016/S1474‑4422(05)70283‑016361023
     [Google Scholar]
  15. TeoK.C. FongS.M. LeungW.C.Y. LeungI.Y.H. WongY.K. ChoiO.M.Y. YamK.K. LoR.C.N. CheungR.T.F. HoS.L. TsangA.C.O. LeungG.K.K. ChanK.H. LauK.K. Location-specific hematoma volume cutoff and clinical outcomes in intracerebral hemorrhage.Stroke20235461548155710.1161/STROKEAHA.122.04124637216445
     [Google Scholar]
  16. KellnerC.P. SongR. AliM. NistalD.A. SamarageM. DangayachN.S. LiangJ. McNeillI. ZhangX. BedersonJ.B. MoccoJ. Time to evacuation and functional outcome after minimally invasive endoscopic intracerebral hemorrhage evacuation.Stroke2021529e536e53910.1161/STROKEAHA.121.03439234424739
     [Google Scholar]
  17. HanleyD.F. ThompsonR.E. RosenblumM. YenokyanG. LaneK. McBeeN. MayoS.W. Bistran-HallA.J. GandhiD. MouldW.A. UllmanN. AliH. CarhuapomaJ.R. KaseC.S. LeesK.R. DawsonJ. WilsonA. BetzJ.F. SugarE.A. HaoY. AvadhaniR. CaronJ.L. HarriganM.R. CarlsonA.P. BultersD. LeDouxD. HuangJ. CobbC. GuptaG. KitagawaR. ChicoineM.R. PatelH. DoddR. CamarataP.J. WolfeS. StadnikA. MoneyP.L. MitchellP. SarabiaR. HarnofS. BarzoP. UnterbergA. TeitelbaumJ.S. WangW. AndersonC.S. MendelowA.D. GregsonB. JanisS. VespaP. ZiaiW. ZuccarelloM. AwadI.A. Abdul-RahimA. Abou-HamdenA. AbrahamM. AhmedA. AlbaC.A. AldrichE.F. AltschulD. Amin-HanjaniS. AndersonD. AnsariS. AntezanaD. ArdeltA. ArikanF. BaguenaM. BakerA. BarrerS.J. BeckerK.J. BergmanT. BoströmA. BraunJ. BrindleyP. BroaddusW.C. BrownR. BukiA. CaoB. CaoY. Carrion-PenagosJ. ChalelaJ. ChangT. ChorroI.M. ChowdhryS. CorralL. CsibaL. DaviesJ. DíazA.T. DerdeynC.P. DiringerM. DlugashR. EckerR. EconomasT. EnriquezP. EzerE. FanY. FengH. FranzD. FreemanW.D. FuscoM. GalicichW. GeleaM.L. GoldsteinJ. GonzalezA.C. GrabaritsC. GreenbergS. GressD. GuE. HallC. HernandezF.M. HoeschR. HohB.L. HouserJ. HuR. HuangY. HussainM.A. InsingaS. JadhavA. JaffeJ. JahromiB.S. JalloJ. JamesM. JamesR.F. JankowitzB. JeonE. JichiciD. JonczakK. JonkerB. KarlenN. KericN. KerzT. KnopmanJ. KoenigC. KrishnamurthyS. KumarA. KureshiI. LaidlawJ. LakhanpalA. LatorreJ.G. LeiferD. LeiphartJ. LeningtonS. LiY. LopezG. LovickD. LumentaC. LuoJ. MaasM.B. MacDonaldJ. MacKenzieL. MadanV. MajkowskiR. MajorO. MalhortaR. MalkoffM. MangatH. MaswadehA. MatoukC. McArthurK. McCaulS. MedowJ. MezeyG. MightyJ. MillerD. MohanK.K. MuirK. MuñozL. NakajiP. NeeA. Nekoovaght-TakS. NyquistP. O’KaneR. OkashaM. O’KellyC. OstapkovichN. PandeyA. Parry-JonesA. PerlaK.R. PollackA. PolsterS. PouratianN. QuinnT. RajajeeV. ReddyK. RehmanM. ReimerR. RinconF. RybinnikI. SanchezB. SansingL. SchneckM. SchuererL. SchulD. SchweitzerJ. SederD.B. SeyfriedD. ShethK. SpiottaA. StechisonM. SzaboK. TamayoG. TanczosK. TausskyP. TerryJ. TestaiF. ThomasK. ThompsonC.B. ThompsonG. TornerJ.C. TranH. TuckerK. UngarL. VarelasP. VargasN.M. VatterH. VenkatasubramanianC. VermillionK. VollmerD. WangY. WangY. WenJ. WhitworthL.T. WillisB. WrencherM. WrightS.E. XuY. YanaseL. YiX. YuZ. ZomorodiA. MISTIE III Investigators Efficacy and safety of minimally invasive surgery with thrombolysis in intracerebral haemorrhage evacuation (MISTIE III): A randomised, controlled, open-label, blinded endpoint phase 3 trial.Lancet2019393101751021103210.1016/S0140‑6736(19)30195‑330739747
     [Google Scholar]
  18. MendelowA.D. GregsonB.A. RowanE.N. MurrayG.D. GholkarA. MitchellP.M. STICH II Investigators Early surgery versus initial conservative treatment in patients with spontaneous supratentorial lobar intracerebral haematomas (STICH II): A randomised trial.Lancet2013382989039740810.1016/S0140‑6736(13)60986‑123726393
     [Google Scholar]
  19. LiX. ChenG. CNS-peripheral immune interactions in hemorrhagic stroke.J. Cereb. Blood Flow Metab.202343218519710.1177/0271678X22114508936476130
     [Google Scholar]
  20. KoenneckeH.C. BelzW. BerfeldeD. EndresM. FitzekS. HamiltonF. KreitschP. MackertB.M. NabaviD.G. NolteC.H. PöhlsW. SchmehlI. SchmitzB. von BrevernM. WalterG. HeuschmannP.U. Berlin Stroke Register Investigators Factors influencing in-hospital mortality and morbidity in patients treated on a stroke unit.Neurology2011771096597210.1212/WNL.0b013e31822dc79521865573
     [Google Scholar]
  21. LvX.N. ShenY.Q. LiZ.Q. DengL. WangZ.J. ChengJ. HuX. PuM.J. YangW.S. XieP. LiQ. Neutrophil percentage to albumin ratio is associated with stroke-associated pneumonia and poor outcome in patients with spontaneous intracerebral hemorrhage.Front. Immunol.202314117371810.3389/fimmu.2023.117371837388726
     [Google Scholar]
  22. WangY. ChenY. ChenR. XuY. ZhengH. XuJ. XiaJ. CaiY. XuH. WangX. Development and validation of a nomogram model for prediction of stroke-associated pneumonia associated with intracerebral hemorrhage.BMC Geriatr.202323163310.1186/s12877‑023‑04310‑537805464
     [Google Scholar]
  23. Becerril-GaitanA. DingD. IronsideN. SoutherlandA.M. WorrallB.B. TestaiF.D. FlahertyM.L. ElkindM.S. KochS. SungG. KittnerS.J. MaysonD.J. GonzalesN. McCauleyJ.L. MalkoffM. HallC.E. FrankelM.R. JamesM.L. AndersonC.D. AronowskiJ. SavitzS.I. WooD. ChenC.J. ERICH investigators Association between body mass index and functional outcomes in patients with intracerebral hemorrhage.Neurology20241022e20801410.1212/WNL.000000000020801438165334
     [Google Scholar]
  24. ShoamaneshA. SelimM. Use of lipid-lowering drugs after intracerebral hemorrhage.Stroke20225372161217010.1161/STROKEAHA.122.03688935658483
     [Google Scholar]
  25. SaitoI. YamagishiK. KokuboY. YatsuyaH. IsoH. SawadaN. InoueM. TsuganeS. Non-high-density lipoprotein cholesterol and risk of stroke subtypes and coronary heart disease: The Japan Public Health Center-Based Prospective (JPHC) study.J. Atheroscler. Thromb.202027436337410.5551/jat.5038531534078
     [Google Scholar]
  26. FalconeG.J. KirschE. AcostaJ.N. NocheR.B. LeasureA. MariniS. ChungJ. SelimM. MeschiaJ.F. BrownD.L. WorrallB.B. TirschwellD.L. JagiellaJ.M. SchmidtH. Jimenez-CondeJ. Fernandez-CadenasI. LindgrenA. SlowikA. GillD. HolmesM. PhuahC.L. PetersenN.H. Matouk MdC.N. GunelM. SansingL. BennettD. ChenZ. SunL.L. ClarkeR. WaltersR.G. GillT.M. BiffiA. KathiresanS. LangefeldC.D. WooD. RosandJ. ShethK.N. AndersonC.D. International Stroke Genetics Consortium Genetically elevated LDL associates with lower risk of intracerebral hemorrhage.Ann. Neurol.2020881566610.1002/ana.2574032277781
     [Google Scholar]
  27. MariniS. CrawfordK. MorottiA. LeeM.J. PezziniA. MoomawC.J. FlahertyM.L. MontanerJ. RoquerJ. Jimenez-CondeJ. Giralt-SteinhauerE. ElosuaR. Cuadrado-GodiaE. Soriano-TarragaC. SlowikA. JagiellaJ.M. PeraJ. UrbanikA. PichlerA. HansenB.M. McCauleyJ.L. TirschwellD.L. SelimM. BrownD.L. SillimanS.L. WorrallB.B. MeschiaJ.F. KidwellC.S. TestaiF.D. KittnerS.J. SchmidtH. EnzingerC. DearyI.J. RannikmaeK. SamarasekeraN. SalmanR.A-S. SudlowC.L. KlijnC.J.M. van NieuwenhuizenK.M. Fernandez-CadenasI. DelgadoP. NorrvingB. LindgrenA. GoldsteinJ.N. ViswanathanA. GreenbergS.M. FalconeG.J. BiffiA. LangefeldC.D. WooD. RosandJ. AndersonC.D. International Stroke Genetics Consortium Association of Apolipoprotein E with intracerebral hemorrhage risk by race/ethnicity.JAMA Neurol.201976448049110.1001/jamaneurol.2018.451930726504
     [Google Scholar]
  28. WooD. DekaR. FalconeG.J. FlahertyM.L. HaverbuschM. MartiniS.R. GreenbergS.M. AyresA.M. SauerbeckL. KisselaB.M. KleindorferD.O. MoomawC.J. AndersonC.D. BroderickJ.P. RosandJ. LangefeldC.D. WooJ.G. Apolipoprotein E, statins, and risk of intracerebral hemorrhage.Stroke201344113013301710.1161/STROKEAHA.113.00130424008570
     [Google Scholar]
/content/journals/cnr/10.2174/0115672026365579241220073506
Loading
Nomogram Models for Predicting Poor Prognosis in Lobar Intracerebral Hemorrhage: A Multicenter Study
Curr Neurovasc Res 21, 595 (2024); https://doi.org/10.2174/0115672026365579241220073506
/content/journals/cnr/10.2174/0115672026365579241220073506
/content/journals/cnr/10.2174/0115672026365579241220073506
Loading

Data & Media loading...

Supplements

Supplementary material is available on the publisher’s website along with the published article.

file format download Download

  • Article Type:     Research Article
Keyword(s): high mortality rate; Lobar intracerebral hemorrhage; nomogram; predictive modeling; prognosis; risk assessment

Most Cited Most Cited RSS feed

This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test