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- ISSN: 1874-4672
- E-ISSN: 1874-4702
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The Role of miR-129-5p in Cancer: A Novel Therapeutic Target
- Source: Current Molecular Pharmacology, Volume 15, Issue 4, Jul 2022, p. 647 - 657
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- 01 Jul 2022
Abstract
miRNA-129-5p belongs to the microRNA-129 (miRNA-129) family. miRNA-129-5p is expressed in many tissues and organs of the human body, and it regulates a wide range of biological functions. The abnormal expression of miRNA-129-5p is related to the occurrence and development of a variety of malignant tumors. miRNA-129-5p plays an important role in the tumorigenesis process and functions by promoting or inhibiting tumors. However, the role of miRNA-129-5p in cancer remains controversial. This article reviews the different biological functions of miRNA- 129-5p in cancer and provides ideas for research in this field to guide the development of targeted therapies and drugs for malignant tumors.
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