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- ISSN: 1874-4672
- E-ISSN: 1874-4702
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Prospective Clinical Applications of CRF Peptide Antagonists
- Source: Current Molecular Pharmacology, Volume 10, Issue 4, Nov 2017, p. 264 - 269
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- 01 Nov 2017
Abstract
It is noteworthy that thirty three years of efforts in corticotropin releasing factor (CRF) research by academia and the pharmaceutical industry resulted in several thousand papers and patents, yet little progress has been made to identify and market diagnostic or therapeutic CRF peptides and small molecule ligands. We document the potential relevance of CRF peptide antagonists to reinvigorate stress/anxiety affected “anatomy systems” in order to boost their efficacy.
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