Current Microwave Chemistry - Volume 10, Issue 2, 2023

Biginelli adducts, also known as dihydropyrimidin-2(1H)-ones/-thiones (DHMPs), exhibit versatile biological activities. Among them, monastrol has gained significant popularity as an inhibitor of kinesin-5 (Eg5), a motor protein crucial for spindle bipolarity. The inhibitory effect of monastrol on Eg5 accounts for its promising anticancer properties, along with its well-established role as an anti-inflammatory agent and calcium channel Read More

Microwave radiation has been utilised since the late 1970s as an alternative thermal energy source for chemical reactions. Initially used in inorganic chemistry, its potential for organic chemistry was revealed in 1986. Convertion of electromagnetic energy into heat, with frequencies ranging from 0.3-300 GHz using microwave irradiation, is an efficient heating method. The microwave heating method has significant potential for ind Read More

This study incorporates the assembly of development methodologies of microwave-activated protocol involving transition metal catalysts for the synthesis of numerous biologically important heterocycles during the past few years. Herein, it highlights the potential of transition metal salts as catalysts in multicomponent reactions performed under microwave conditions for the formation of oxygen, nitrogen, and sulphur-contai Read More

One of the most efficient non-conventional heating methods is microwave irradiation. In organic synthesis, microwave irradiation has become a popular heating technique as it enhances product yields and purities, reduces reaction time from hours to minutes, and decreases unwanted side reactions. Microwave-assisted organic synthesis utilizes dielectric volumetric heating as an alternative activation method, which results i Read More

One of the most efficient non-conventional heating methods is microwave irradiation. In organic synthesis, microwave irradiation has become a popular heating technique as it enhances product yields and purities, reduces reaction time from hours to minutes, and decreases unwanted side reactions. Microwave-assisted organic synthesis utilizes dielectric volumetric heating as an alternative activation method, which results i Read More

Peptides are important as drugs and biologically active molecules. The synthesis of peptides has gathered considerable attention in recent years due to their various attractive properties. Conventional peptide synthesis is tedious and requires hazardous reagents and solvents. Microwave- assisted solid-phase peptide synthesis has several advantages compared with conventional batch synthesis. Herein, we have discussed v Read More

Microwave-assisted synthesis is a powerful tool in organic chemistry, providing a rapid and efficient method for the synthesis of bioactive heterocycles. The application of microwaves significantly reduces reaction times and increases percentage yields with high purity of the final product. To make the synthetic protocol greener, the application of the magnetic nanocatalyst is a rapidly growing area of interest nowa Read More

The microwave chemistry of several bioactive natural products and synthetic compounds was studied by us. The compounds of different types, such as alkaloid, terpenoid, lignan, etc. were considered for our investigation. Some indole compounds, as well as organosulfur and miscellaneous carbonyl compounds, were also included. The substrates were irradiated under microwave irradiation for a short time and the resulting Read More

Background: Tuberculosis is an effectual infectious disease caused by the spread of tubercular bacteria within the lungs via droplets of coughs and sneezes. In 2021, 1.6 million people died due totuberculosis, which is the 13th leading killer disease and 2nd leading after COVID-19 infectious disease.Objective: Many drugs are available as antitubercular drug, but still, requires more efficacious drug molecules with lower toxicity Read More

Aim: This is a comparative study of some new coumarin substituted thioaryl pyrazolyl pyrazoline.Methods: The target compounds were synthesized using both conventional as well as microwave irradiation by reaction of coumarin chalcones with different substituted hydrazine hydrates and aryl hydrazines to give the resultant pyrazoline derivatives. Microwave reaction, enhanced organic reactions, and reduced reaction time led Read More

Lignin is a very abundant biopolymer with great potential to produce other high-value polymers with aromatic groups. Its valorization has been limited principally by its poor solubility in conventional organic solvents, which makes it difficult to deconstruct or transform it into other products with higher added value. In this work, we describe a one-pot procedure to prepare various Deep Eutectic Solvents and study their ability Read More

Background: The characteristics of matter and the dynamics of molecular processes are examined by acoustic approaches. The primary techniques in molecular acoustics are the measurement of sound speed and sound absorption, as well as the relationship between these quantities and different physical variables including pressure, temperature, and wave frequency. Molecular acoustics emerged as a separate field i Read More