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2000
Volume 20, Issue 3
  • ISSN: 1573-4021
  • E-ISSN: 1875-6506

Abstract

Gestational hypertension and preeclampsia are frequently encountered conditions in pregnancy, often occurring around the time of delivery. Mild cases of these conditions in the near term typically result in few complications for both the mother and the newborn. However, women diagnosed with gestational hypertension or preeclampsia need careful monitoring of both maternal and fetal well-being throughout pregnancy, and those with severe symptoms should receive hospital-based management. Preeclampsia is associated with endothelial dysfunction in the mother, prolonged immunological activation, fetal development limitation, hypertension with or without proteinuria, and endothelial dysfunction after week twenty of pregnancy. Pregnancy-related hypertension raises concerns, although the main issues are related to the progression of the condition to pre-eclampsia or eclampsia and HELLP syndrome. In this review, the cross-sectional study of gestational hypertension is evaluated, and the treatment approaches are highlighted.

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2025-07-28

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References

  1. ManciaG. FagardR. NarkiewiczK. RedonJ. ZanchettiA. BöhmM. ChristiaensT. CifkovaR. De BackerG. DominiczakA. GalderisiM. 2013 ESH/ESC guidelines for the management of arterial hypertension.Arterial Hypertens.201317269168
     [Google Scholar]
  2. WheltonP.K. CareyR.M. AronowW.S. CaseyD.E.Jr CollinsK.J. Dennison HimmelfarbC. DePalmaS.M. GiddingS. JamersonK.A. JonesD.W. MacLaughlinE.J. MuntnerP. OvbiageleB. SmithS.C.Jr SpencerC.C. StaffordR.S. TalerS.J. ThomasR.J. WilliamsK.A.Sr WilliamsonJ.D. WrightJ.T.Jr Force on clinical practice guidelines.Hypertension20187161269132410.1161/HYP.000000000000006629133354
     [Google Scholar]
  3. CareyR.M. MuntnerP. BosworthH.B. WheltonP.K. Prevention and control of hypertension: JACC health promotion series.J. Am. Coll. Cardiol.201872111278129310.1016/j.jacc.2018.07.00830190007
     [Google Scholar]
  4. VRAGHU Prevalence and patterns of cardiovascular risk factors in young hypertensive patients.DJCM.2024632
     [Google Scholar]
  5. NjugunaJ. Planned delivery at 37 weeks gestation versus expectant management for non-severe chronic hypertension, a systematic review.A dissertation submitted in part fulfillment of the requirements for the degree of Master of Medicine In Obstetrics and Gynecology2021
     [Google Scholar]
  6. MennittoS. Associations between mindfulness, psychological health and aspects of cardiovascular function in pregnancy.McGill UniversityCanada2022
     [Google Scholar]
  7. WuX.Y. LiZ.L. WuC.Y. LiuY.M. LinH. WangS.H. XiaoW.F. Endocrine traits of polycystic ovary syndrome in prenatally androgenized female Sprague-Dawley rats.Endocr. J.201057320120910.1507/endocrj.K09E‑20520057162
     [Google Scholar]
  8. LeiJ. ZhaoM. LiL. JiB. XuT. SunM. Research progress of placental vascular pathophysiological changes in pregnancy-induced hypertension and gestational diabetes mellitus.Frontiers Media S.A.2022Vol. 13
     [Google Scholar]
  9. HamadRN ZanganaJM Comparing non-stress test versus Umbilical Artery doppler velocimetry among Aample of high-risk pregnant women in Erbil city.BJMS202310.3329/bjms.v22i20.66301
     [Google Scholar]
  10. AdoM.S. SuwaidM.A. DambattaA.H. LawalY. Sonographic estimation of gestational age using transverse cerebellar diameter among late trimester pregnancies in Kano, Northwest Nigeria.West Afr. J. Radiol.2023301202510.4103/wajr.wajr_2_24
     [Google Scholar]
  11. GudetaT.A. RegassaT.M. Pregnancy induced hypertension and associated factors among women attending delivery service at mizan-tepi university teaching hospital, tepi general hospital and gebretsadik shawo hospital, southwest, Ethiopia.Ethiop. J. Health Sci.201929183184030700950
     [Google Scholar]
  12. BraunthalS. BrateanuA. Hypertension in pregnancy: Pathophysiology and treatment.SAGE Open Med.20197205031211984370010.1177/205031211984370031007914
     [Google Scholar]
  13. CesneA.L. JudsonI. MakiR. GrossoF. SchuetzeS. MehrenM.V. ChawlaS.P. DemetriG.D. NietoA. TanovicA. BlayJ-Y. Trabectedin is a feasible treatment for soft tissue sarcoma patients regardless of patient age: A retrospective pooled analysis of five phase II trials.Br. J. Cancer201310971717172410.1038/bjc.2013.52424022187
     [Google Scholar]
  14. PaddaJ. KhalidK. ColacoL.B. PaddaS. BoddetiN.L. KhanA.S. CooperA.C. Jean-CharlesG. Efficacy of magnesium sulfate on maternal mortality in eclampsia.Cureus2021138e1732210.7759/cureus.1732234567870
     [Google Scholar]
  15. TadicM. CuspidiC. Suzic LazicJ. VukomanovicV. MihajlovicS. SavicP. CvrkoticM. GrassiG. CelicV. Blood pressure variability correlates with right ventricular strain in women with gestational hypertension and preeclampsia.J. Hum. Hypertens.202236982683210.1038/s41371‑021‑00580‑x34272473
     [Google Scholar]
  16. HamiltonBE MartinJA OstermanMJ RossenLM Births: Provisional data for 20182018Available from: https://www.cdc.gov/nchs/data/vsrr/vsrr-007-508.pdf
  17. GoldsteinR.F. AbellS.K. RanasinhaS. MissoM. BoyleJ.A. BlackM.H. LiN. HuG. CorradoF. RodeL. KimY.J. HaugenM. SongW.O. KimM.H. BogaertsA. DevliegerR. ChungJ.H. TeedeH.J. Association of gestational weight gain with maternal and infant outcomes: A systematic review and meta-analysis.JAMA2017317212207222510.1001/jama.2017.363528586887
     [Google Scholar]
  18. VoermanE. SantosS. InskipH. AmianoP. BarrosH. CharlesM.A. ChatziL. ChrousosG.P. CorpeleijnE. CrozierS. DoyonM. EggesbøM. FantiniM.P. FarchiS. ForastiereF. GeorgiuV. GoriD. HankeW. Hertz-PicciottoI. HeudeB. HivertM.F. HryhorczukD. IñiguezC. KarvonenA.M. KüpersL.K. LagströmH. LawlorD.A. LehmannI. MagnusP. MajewskaR. MäkeläJ. ManiosY. MommersM. MorgenC.S. MoschonisG. NohrE.A. Nybo AndersenA.M. OkenE. PacA. PapadopoulouE. PekkanenJ. PizziC. PolanskaK. PortaD. RichiardiL. Rifas-ShimanS.L. RoeleveldN. RonfaniL. SantosA.C. StandlM. StigumH. StoltenbergC. ThieringE. ThijsC. TorrentM. TrnovecT. van GelderM.M.H.J. van RossemL. von BergA. VrijheidM. WijgaA. ZvinchukO. SørensenT.I.A. GodfreyK. JaddoeV.W.V. GaillardR. Association of gestational weight gain with adverse maternal and infant outcomes.JAMA2019321171702171510.1001/jama.2019.382031063572
     [Google Scholar]
  19. HalesC.M. FryarC.D. CarrollM.D. FreedmanD.S. OgdenC.L. Trends in obesity and severe obesity prevalence in US youth and adults by sex and age, 2007-2008 to 2015-2016.JAMA2018319161723172510.1001/jama.2018.306029570750
     [Google Scholar]
  20. KahanS. MansonJ.E. Obesity treatment, beyond the guidelines: Practical suggestions for clinical practice.JAMA2019321141349135010.1001/jama.2019.235230896727
     [Google Scholar]
  21. CurryS.J. KristA.H. OwensD.K. BarryM.J. CaugheyA.B. DavidsonK.W. DoubeniC.A. EplingJ.W.Jr GrossmanD.C. KemperA.R. KubikM. LandefeldC.S. MangioneC.M. PhippsM.G. SilversteinM. SimonM.A. TsengC.W. WongJ.B. Behavioral weight loss interventions to prevent obesity-related morbidity and mortality in adults: US Preventive Services Task Force recommendation statement.JAMA2018320111163117110.1001/jama.2018.1302230326502
     [Google Scholar]
  22. SibaiB.M. Hypertension in pregnancy.Obstet. Gynecol. Clin. North Am.199219461563210.1016/S0889‑8545(21)00610‑01484651
     [Google Scholar]
  23. PannuH.K. OliphantM. The subperitoneal space and peritoneal cavity: Basic concepts.Abdom. Imaging20154072710272210.1007/s00261‑015‑0429‑526006061
     [Google Scholar]
  24. KalraA WehrleCJ TumaF Anatomy, abdomen and pelvis, peritoneum.StatPearls publishing2023
     [Google Scholar]
  25. SalmaniD. PurushothamanS. SomashekaraS. GnanagurudasanE. SumangaladeviK. HarikishanR. VenkateshwarareddyM. Study of structural changes in placenta in pregnancy-induced hypertension.J. Nat. Sci. Biol. Med.20145235235510.4103/0976‑9668.13618225097413
     [Google Scholar]
  26. JaimanS. RomeroR. PacoraP. JungE. BhattiG. YeoL. KimY.M. KimB. KimC.J. KimJ.S. QureshiF. JacquesS.M. ErezO. Gomez-LopezN. HsuC.D. Disorders of placental villous maturation in fetal death.J. Perinat. Med.20200034536810.1515/jpm‑2020‑003032238609
     [Google Scholar]
  27. ChristiansJ.K. GrynspanD. Placental villous hypermaturation is associated with improved neonatal outcomes.Placenta2019761510.1016/j.placenta.2019.01.01230803708
     [Google Scholar]
  28. SalmaniJ. AsgharS. LvH. ZhouJ. Aqueous solubility and degradation kinetics of the phytochemical anticancer thymoquinone; probing the effects of solvents, pH and light.Molecules20141955925593910.3390/molecules1905592524815311
     [Google Scholar]
  29. AgrawalA.F. WangA.D. Increased transmission of mutations by low-condition females: Evidence for condition-dependent DNA repair.PLoS Biol.200862e3010.1371/journal.pbio.006003018271627
     [Google Scholar]
  30. VanWijkM. KublickieneK. BoerK. VanBavelE. Vascular function in preeclampsia.Cardiovasc. Res.2000471384810.1016/S0008‑6363(00)00087‑010869528
     [Google Scholar]
  31. LosadaA. HiranoM. HiranoT. Cohesin release is required for sister chromatid resolution, but not for condensin-mediated compaction, at the onset of mitosis.Genes Dev.200216233004301610.1101/gad.24920212464631
     [Google Scholar]
  32. HerseF. DechendR. HarsemN.K. WallukatG. JankeJ. QadriF. HeringL. MullerD.N. LuftF.C. StaffA.C. Dysregulation of the circulating and tissue-based renin-angiotensin system in preeclampsia.Hypertension200749360461110.1161/01.HYP.0000257797.49289.7117261642
     [Google Scholar]
  33. FuruyaR.S. CesaroniR. TakahashiS. CodellaC. MomoseM. BeltránM.T. Candidate rotating toroids around high-mass (proto) stars.Astrophys. J.2008673136338110.1086/523834
     [Google Scholar]
  34. FuruyaT. KamletA.S. RitterT. Catalysis for fluorination and trifluoromethylation.Nature2011473734847047710.1038/nature1010821614074
     [Google Scholar]
  35. KhongTY Placental vascular development and neonatal outcomeSemin Neonatol20049425526310.1016/j.siny.2003.11.010
     [Google Scholar]
  36. LianR. ZhuB.S. ZengX. An update review of the pathogenesis hypothesis in preeclampsia.Clin. Exp. Obstet. Gynecol.202249817010.31083/j.ceog4908170
     [Google Scholar]
  37. HarmonA.C. CorneliusD.C. AmaralL.M. FaulknerJ.L. CunninghamM.W.Jr WallaceK. LaMarcaB. The role of inflammation in the pathology of preeclampsia.Clin. Sci. (Lond.)2016130640941910.1042/CS2015070226846579
     [Google Scholar]
  38. JungE. RomeroR. YeoL. Gomez-LopezN. ChaemsaithongP. JaovisidhaA. GotschF. ErezO. The etiology of preeclampsia.Am. J. Obstet. Gynecol.20222262S844S86610.1016/j.ajog.2021.11.135635177222
     [Google Scholar]
  39. CorneliusDC Preeclampsia: From inflammation to immunoregulationClin Med Insights Blood Disord2018111179545X1775232510.1177/1179545X17752325
     [Google Scholar]
  40. ChangK.J. SeowK.M. ChenK.H. Preeclampsia: Recent advances in predicting, preventing, and managing the maternal and fetal life-threatening condition.Int. J. Environ. Res. Public Health2023204299410.3390/ijerph2004299436833689
     [Google Scholar]
  41. LongoS.A. DolaC.P. PridjianG. Preeclampsia and eclampsia revisited.South. Med. J.200396989189910.1097/01.SMJ.0000084385.85123.0814513987
     [Google Scholar]
  42. OżarowskiM. MikołajczakP.Ł. KujawskiR. WielgusK. KlejewskiA. WolskiH. Seremak-MrozikiewiczA. Pharmacological effect of quercetin in hypertension and its potential application in pregnancy-induced hypertension: Review of in vitro, in vivo, and clinical studies.Evid. Based Complement. Alternat. Med.201820181742148910.1155/2018/742148930622610
     [Google Scholar]
  43. BharadwajS.K. Vishnu BhatB. VickneswaranV. AdhisivamB. BobbyZ. HabeebullahS. Oxidative stress, antioxidant status and neurodevelopmental outcome in neonates born to pre-eclamptic mothers.Indian J. Pediatr.201885535135710.1007/s12098‑017‑2560‑529264827
     [Google Scholar]
  44. SavitzD.A. DanilackV.A. EngelS.M. ElstonB. LipkindH.S. Descriptive epidemiology of chronic hypertension, gestational hypertension, and preeclampsia in New York State, 1995-2004.Matern. Child Health J.201418482983810.1007/s10995‑013‑1307‑923793484
     [Google Scholar]
  45. SchneiderS. FreerksenN. MaulH. RoehrigS. FischerB. HoeftB. Risk groups and maternal-neonatal complications of preeclampsia – Current results from the national German Perinatal Quality Registry.J. Perinat. Med.201139325726510.1515/jpm.2011.01021309631
     [Google Scholar]
  46. KlungsøyrK. MorkenN.H. IrgensL. VollsetS.E. SkjærvenR. Secular trends in the epidemiology of pre-eclampsia throughout 40 years in Norway: Prevalence, risk factors and perinatal survival.Paediatr. Perinat. Epidemiol.201226319019810.1111/j.1365‑3016.2012.01260.x22471678
     [Google Scholar]
  47. TimpkaS. MarkovitzA. SchymanT. MogrenI. FraserA. FranksP.W. Rich-EdwardsJ.W. Midlife development of type 2 diabetes and hypertension in women by history of hypertensive disorders of pregnancy.Cardiovasc. Diabetol.201817112410.1186/s12933‑018‑0764‑230200989
     [Google Scholar]
  48. CatovJM CountourisM HauspurgA Hypertensive disorders of pregnancy and CVD prediction: Accounting for risk accrual during the reproductive yearsJ Am Coll Cardiol2018721112641266
     [Google Scholar]
  49. RazzakR. ShivkumarP.V. Early prediction of hypertensive diseases of pregnancy by using combined screening methods in a rural population.Cureus20231512e5062410.7759/cureus.5062438226112
     [Google Scholar]
  50. RadparvarA.A. VaniK. FioriK. Hypertensive disorders of pregnancy: Innovative management strategiesJACC Adv202433100864
     [Google Scholar]
  51. YangYY FangYH WangX ZhangY LiuXJ YinZZ A retrospective cohort study of risk factors and pregnancy outcomes in 14,014 Chinese pregnant womenMedicine (Baltimore)20189733e11748
     [Google Scholar]
  52. NoronhaJ.A. BhaduriA. BhatH.V. KamathA. Maternal risk factors and anaemia in pregnancy: A prospective retrospective cohort study.J. Obstet. Gynaecol.201030213213610.3109/0144361090326745720143970
     [Google Scholar]
  53. RobertsJM PearsonG CutlerJ LindheimerM Summary of the NHLBI working group on research on hypertension during pregnancyHypertens Pregnancy2003222109127
     [Google Scholar]
  54. KoualM. AbbouH. CarbonnelM. PiconeO. AyoubiJ.M. Short-term outcome of patients with preeclampsia.Vasc. Health Risk Manag.2013914314823610524
     [Google Scholar]
  55. CoghillA.E. HansenS. LittmanA.J. Risk factors for eclampsia: A population-based study in Washington State, 1987–2007.Am. J. Obstet. Gynecol.20112056553.e1553.e710.1016/j.ajog.2011.06.07921855842
     [Google Scholar]
  56. AndersonN.H. SadlerL.C. StewartA.W. FyfeE.M. McCowanL.M.E. Ethnicity, body mass index and risk of pre-eclampsia in a multiethnic N ew Z ealand population.Aust. N. Z. J. Obstet. Gynaecol.201252655255810.1111/j.1479‑828X.2012.01475.x23020751
     [Google Scholar]
  57. BartschE. MedcalfK.E. ParkA.L. RayJ.G. Clinical risk factors for pre-eclampsia determined in early pregnancy: Systematic review and meta-analysis of large cohort studies.BMJ2016353i175310.1136/bmj.i175327094586
     [Google Scholar]
  58. BenerA. SalehN.M. The impact of socio-economic, lifestyle habits, and obesity in developing of pregnancy-induced hypertension in fast-growing country: Global comparisons.Clin. Exp. Obstet. Gynecol.2013401525723724507
     [Google Scholar]
  59. LučovnikM. TulN. VerdenikI. NovakŽ. BlicksteinI. Risk factors for preeclampsia in twin pregnancies: A population-based matched case-control study.J. Perinat. Med.201240437938210.1515/jpm‑2011‑025222752768
     [Google Scholar]
  60. MostelloD. CatlinT.K. RomanL. HolcombW.L.Jr LeetT. Preeclampsia in the parous woman: Who is at risk?Am. J. Obstet. Gynecol.2002187242542910.1067/mob.2002.12360812193937
     [Google Scholar]
  61. DalmázC.A. dos SantosK.G. BottonM.R. RoisenbergI. Fatores de risco para distúrbios hipertensivos durante a gravidez no Sul do Brasil.Rev. Assoc. Med. Bras.201157669269622249551
     [Google Scholar]
  62. MelamedN. HadarE. PeledY. HodM. WiznitzerA. YogevY. Risk for recurrence of preeclampsia and outcome of subsequent pregnancy in women with preeclampsia in their first pregnancy.J. Matern. Fetal Neonatal Med.201225112248225110.3109/14767058.2012.68417422524456
     [Google Scholar]
  63. DanzaA. Ruiz-IrastorzaG. KhamashtaM. Antiphospohlipid syndrome in obstetrics.Best Pract. Res. Clin. Obstet. Gynaecol.2012261657610.1016/j.bpobgyn.2011.10.00622079775
     [Google Scholar]
  64. ClarkE.A.S. SilverR.M. Ware BranchD. Do antiphospholipid antibodies cause preeclampsia and HELLP syndrome?Curr. Rheumatol. Rep.20079321922510.1007/s11926‑007‑0035‑917531175
     [Google Scholar]
  65. WeiS.Q. QiH.P. LuoZ.C. FraserW.D. Maternal vitamin D status and adverse pregnancy outcomes: A systematic review and meta-analysis.J. Matern. Fetal Neonatal Med.201326988989910.3109/14767058.2013.76584923311886
     [Google Scholar]
  66. TabeshM. Salehi-AbargoueiA. TabeshM. EsmaillzadehA. Maternal vitamin D status and risk of pre-eclampsia: A systematic review and meta-analysis.J. Clin. Endocrinol. Metab.20139883165317310.1210/jc.2013‑125723783101
     [Google Scholar]
  67. YangJ.D. HainautP. GoresG.J. AmadouA. PlymothA. RobertsL.R. A global view of hepatocellular carcinoma: Trends, risk, prevention and management.Nat. Rev. Gastroenterol. Hepatol.2019161058960410.1038/s41575‑019‑0186‑y31439937
     [Google Scholar]
  68. IraniM. AradmehrM. GhorbaniM. BaghaniR. Electromagnetic field exposure and abortion in pregnant women: A systematic review and meta-analysis.Malays. J. Med. Sci.2023305708010.21315/mjms2023.30.5.637928787
     [Google Scholar]
  69. PolakG. BednarekW. WertelI. Endometriosis in adolescents.Springer2013
     [Google Scholar]
  70. Agbayani CruzC.T.A. BucuM.E.M. Clinical profile and symptoms of young women aged 10–24 years diagnosed with pelvic endometriosis: A 5-year experience of a tertiary hospital in the Philippines.Journal of Endometriosis and Uterine Disorders2024810008510.1016/j.jeud.2024.100085
     [Google Scholar]
  71. SinghS. SolimanA.M. RahalY. RobertC. DefoyI. NisbetP. LeylandN. Prevalence, symptomatic burden, and diagnosis of Endometriosis in Canada: Cross-sectional survey of 30 000 women.J. Obstet. Gynaecol. Can.202042782983810.1016/j.jogc.2019.10.03832001176
     [Google Scholar]
  72. MissmerS.A. TuF. SolimanA.M. ChiuveS. CrossS. EichnerS. Antunez FloresO. HorneA. SchneiderB. As-SanieS. Impact of endometriosis on women’s life decisions and goal attainment: A cross-sectional survey of members of an online patient community.BMJ Open2022124e05276510.1136/bmjopen‑2021‑05276535477879
     [Google Scholar]
  73. MatthysL.A. CoppageK.H. LambersD.S. BartonJ.R. SibaiB.M. Delayed postpartum preeclampsia: An experience of 151 cases.Am. J. Obstet. Gynecol.200419051464146610.1016/j.ajog.2004.02.03715167870
     [Google Scholar]
  74. YanceyL.M. WithersE. BakesK. AbbottJ. Postpartum preeclampsia: Emergency department presentation and management.J. Emerg. Med.201140438038410.1016/j.jemermed.2008.02.05618814997
     [Google Scholar]
  75. GhumanN. RheinerJ. TendlerB.E. WhiteW.B. Hypertension in the postpartum woman: Clinical update for the hypertension specialist.J. Clin. Hypertens. (Greenwich)2009111272673310.1111/j.1751‑7176.2009.00186.x
     [Google Scholar]
  76. MakrisA. ThorntonC. HennessyA. Postpartum hypertension and nonsteroidal analgesia.Am. J. Obstet. Gynecol.2004190257757810.1016/j.ajog.2003.08.03014981414
     [Google Scholar]
  77. WasdenS.W. RagsdaleE.S. ChasenS.T. SkupskiD.W. Impact of non-steroidal anti-inflammatory drugs on hypertensive disorders of pregnancy.Pregnancy Hypertens.20144425926310.1016/j.preghy.2014.06.00126104814
     [Google Scholar]
  78. Vigil-De GraciaP. SolisV. OrtegaN. Ibuprofen versus acetaminophen as a post-partum analgesic for women with severe pre-eclampsia: Randomized clinical study.J. Matern. Fetal Neonatal Med.201730111279128210.1080/14767058.2016.121059927384376
     [Google Scholar]
  79. BlueN.R. Murray-KrezanC. Drake-LavelleS. WeinbergD. HolbrookB.D. KatukuriV.R. LeemanL. MozurkewichE.L. Effect of ibuprofen vs acetaminophen on postpartum hypertension in preeclampsia with severe features: A double-masked, randomized controlled trial.Am. J. Obstet. Gynecol.20182186616.e1616.e810.1016/j.ajog.2018.02.01629505772
     [Google Scholar]
  80. DarteyA.F. DzansiG. LotseC.W. ObuobisaR. Afua BosuC.E. AfayaA. Midwives experiences of managing clients with eclampsia in a low resource setting: A qualitative descriptive study.SAGE Open Nurs.202282377960822109454210.1177/2377960822109454235600007
     [Google Scholar]
  81. TitaA.T. SzychowskiJ.M. BoggessK. DugoffL. SibaiB. LawrenceK. HughesB.L. BellJ. AagaardK. EdwardsR.K. GibsonK. HaasD.M. PlanteL. MetzT. CaseyB. EsplinS. LongoS. HoffmanM. SaadeG.R. HoppeK.K. ForoutanJ. TuuliM. OwensM.Y. SimhanH.N. FreyH. RosenT. PalatnikA. BakerS. AugustP. ReddyU.M. KinzlerW. SuE. KrishnaI. NguyenN. NortonM.E. SkupskiD. El-SayedY.Y. OgunyemiD. GalisZ.S. HarperL. AmbalavananN. GellerN.L. OparilS. CutterG.R. AndrewsW.W. Treatment for mild chronic hypertension during pregnancy.N. Engl. J. Med.2022386191781179210.1056/NEJMoa220129535363951
     [Google Scholar]
  82. CeresR ModroñoA RuízS LindheimerMD SibaiB Doppler velocimetry: Is it useful in preeclampsia?AJOG2001185522523
     [Google Scholar]
  83. ContraceptionE. Practice bulletin clinical management guidelines for obstetrician–gynecologISTS.Obstet. Gynecol.201841
     [Google Scholar]
  84. ACOG Practice Bulletin. Clinical management guidelines for Obstetrician-Gynecologists use of psychiatric medications during pregnancy and Lactation.Focus20097338540010.1176/foc.7.3.foc385
     [Google Scholar]
  85. GasnierR. ValérioE.G. Lopes RamosJ.G. Antihypertensive drugs in pregnancy.Fam. Med. Community Health201311375010.15212/FMCH.2013.0106
     [Google Scholar]
  86. KumariA. RohatgiR. SinghA. KumarR. Comparative study of intravenous hydralazine and labetalol in severe hypertensive disorders of pregnancy.Int. J. Reprod. Contracept. Obstet. Gynecol.20209267510.18203/2320‑1770.ijrcog20200357
     [Google Scholar]
  87. BoothJ.N. AnsteyD.E. BelloN.A. JaegerB.C. PuglieseD.N. ThomasS.J. DengL. ShikanyJ.M. Lloyd-JonesD. SchwartzJ.E. LewisC.E. ShimboD. MuntnerP. Race and sex differences in asleep blood pressure: The coronary artery risk development in young adults (CARDIA) study.J. Clin. Hypertens. (Greenwich)201921218419210.1111/jch.1347430719843
     [Google Scholar]
  88. GucluS. GolM. SaygiliU. DemirN. SezerO. BaschatA.A. Nifedipine therapy for preterm labor: Effects on placental, fetal cerebral and atrioventricular Doppler parameters in the first 48 hours.Ultrasound Obstet. Gynecol.200627440340810.1002/uog.272816565996
     [Google Scholar]
  89. BrownM.A. MageeL.A. KennyL.C. KarumanchiS.A. McCarthyF.P. SaitoS. Hypertensive disorders of pregnancy: ISSHP classification, diagnosis, and management recommendations for international practiceHypertension20187212443
     [Google Scholar]
  90. MageeL.A. PelsA. HelewaM. ReyE. Von DadelszenP. Diagnosis, evaluation, and management of the hypertensive disorders of pregnancy.Pregnancy Hypertension. Elsevier B.V.2014Vol. 4105145
     [Google Scholar]
  91. KattahA.G. GarovicV.D. The management of hypertension in pregnancy.Adv. Chronic Kidney Dis.201320322923910.1053/j.ackd.2013.01.01423928387
     [Google Scholar]
  92. Poniedziałek-CzajkowskaE. MierzyńskiR. DłuskiD. Leszczyńska-GorzelakB. Prevention of hypertensive disorders of pregnancy—Is there a place for Metformin?J. Clin. Med.20211013280510.3390/jcm1013280534202343
     [Google Scholar]
  93. GarovicV.D. DechendR. EasterlingT. KarumanchiS.A. BairdS.M.M. MageeL.A. Hypertension in pregnancy: Diagnosis, blood pressure goals, and Pharmacotherapy: A scientific statement from the american heart associationHypertension2022792e21e41
     [Google Scholar]
  94. BeechA. MangosG. Management of hypertension in pregnancy.Aust. Prescr.202144514815210.18773/austprescr.2021.03934728879
     [Google Scholar]
  95. PoonL.C. MageeL.A. VerlohrenS. ShennanA. von DadelszenP. SheinerE. HadarE. VisserG. Da Silva CostaF. KapurA. McAuliffeF. NazarethA. TahlakM. KiharaA.B. DivakarH. McIntyreH.D. BerghellaV. YangH. RomeroR. NicolaidesK.H. MelamedN. HodM. A literature review and best practice advice for second and third trimester risk stratification, monitoring, and management of pre-eclampsia.Int. J. Gynaecol. Obstet.2021154S1Suppl. 133110.1002/ijgo.1376334327714
     [Google Scholar]
  96. RanaS. LemoineE. GrangerJ.P. KarumanchiS.A. Preeclampsia.Circ. Res.201912471094111210.1161/CIRCRESAHA.118.31327630920918
     [Google Scholar]
  97. HauthJ.C. EwellM.G. LevineR.J. EsterlitzJ.R. SibaiB. CuretL.B. CatalanoP.M. MorrisC.D. Pregnancy outcomes in healthy nulliparas who developed hypertension.Obstet. Gynecol.2000951242810636496
     [Google Scholar]
  98. KnuistM. BonselG.J. ZondervanH.A. TreffersP.E. Intensification of fetal and maternal surveillance in pregnant women with hypertensive disorders.Int. J. Gynaecol. Obstet.199861212713310.1016/S0020‑7292(98)00024‑19639216
     [Google Scholar]
  99. ChenM.H. A systematic review of the blood pressure lowering efficacy of diuretics as second-line therapy for primary hypertensionUniversity of British Columbia
     [Google Scholar]
  100. SibaiB.M. HauthJ. CaritisS. LindheimerM.D. MacPhersonC. KlebanoffM. VanDorstenJ.P. LandonM. MiodovnikM. PaulR. MeisP. ThurnauG. DombrowskiM. RobertsJ. McNellisD. Hypertensive disorders in twin versus singleton gestations.Am. J. Obstet. Gynecol.2000182493894210.1016/S0002‑9378(00)70350‑410764477
     [Google Scholar]
  101. BuchbinderA. SibaiB.M. CaritisS. MacPhersonC. HauthJ. LindheimerM.D. KlebanoffM. VanDorstenP. LandonM. PaulR. MiodovnikM. MeisP. ThurnauG. Adverse perinatal outcomes are significantly higher in severe gestational hypertension than in mild preeclampsia.Am. J. Obstet. Gynecol.20021861667110.1067/mob.2002.12008011810087
     [Google Scholar]
/content/journals/chyr/10.2174/0115734021312990241115045601
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Gestational Hypertension: A Contemporary Review of Epidemiology, Pathophysiology, and Therapeutic Approaches
Current Hypertension Reviews 20, 117 (2024); https://doi.org/10.2174/0115734021312990241115045601
/content/journals/chyr/10.2174/0115734021312990241115045601
/content/journals/chyr/10.2174/0115734021312990241115045601
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  • Article Type:     Review Article
Keyword(s): elevated liver enzymes and low platelets; Gestational hypertension; hemolysis; preeclampsia; pregnancy induced hypertension; proteinuria

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