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2000
Volume 14, Issue 2
  • ISSN: 1574-8863
  • E-ISSN: 2212-3911

Abstract

Background: Metronidazole, a widely used antibacterial and antiprotozoal drug, is often the drug of choice in amoebic liver abscess. The drug, otherwise safe, can cause serious central nervous disturbances in rare circumstances. Case Report: Here, we report a case of cerebellar dysfunction in the form of slurring of speech and episodes of falls, in an elderly male following a three-week course of metronidazole therapy. Results and Conclusion: The patient manifested classic radiologic features of metronidazole neurotoxicity. Marked improvement in clinical symptoms was seen following drug discontinuation.

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/content/journals/cds/10.2174/1574886314666190206154735
2019-07-01
2025-07-08
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  • Article Type:
    Case Report
Keyword(s): amoebiasis; CSF; neurotoxicity; Nitro imidazole; pharmacogenetics; pharmacovigilance
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