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2000
Volume 14, Issue 2
  • ISSN: 1574-8863
  • E-ISSN: 2212-3911

Abstract

Background: Drug hypersensitivity reactions to infliximab have been reported in pediatric patients. At times, these patients may need infliximab administration in spite of hypersensitivity. However, only a few reports of desensitization protocols are available in the literature in pediatric patients. Case Report: We report a case of immediate hypersensitivity reaction to intravenous infliximab in a 13-year-old child suffering from pustular psoriasis who eventually underwent a 14 step desensitization protocol for the administration of infliximab in a pediatric intensive care unit. Results and Conclusion: Although our desensitization protocol was safe and effective, we recommend the entire desensitization procedure to be performed under the supervision of experienced personnel in a pediatric intensive care unit. Future studies with larger sample size are needed to confirm our findings.

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/content/journals/cds/10.2174/1574886314666190119115632
2019-07-01
2025-07-13
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/content/journals/cds/10.2174/1574886314666190119115632
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  • Article Type:
    Case Report
Keyword(s): BAT; Desensitization; infliximab; monoclonal antibody; pediatric; psoriasis
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