Current Diabetes Reviews - Volume 6, Issue 2, 2010

Overweight and obesity is a growing “world-wide epidemic problem”. Because as many as, two-third of the adult population and a growing number of children are overweight. The prevalence of diabetes, especially type 2 diabetes and hypertension have significantly increased with the prevalence of obesity. Obesity accompanying type 2 diabetes and hypertension are known to be closely linked with insulin resistance an Read More

In recent years, the number of people suffering from diabetes has increased notably. This increase has led to an augmentation in secondary diseases; amongst them, diabetic nephropathy (DN) is one of the most relevant pathologies. DN provokes a decrease in glomerular filtration rate, which ends up in chronic renal failure. In the developed countries, DN is the first cause of chronic renal failure needing replacement ther Read More

Diabetes mellitus is a group of metabolic disorders of carbohydrate metabolism in which glucose is underutilized, producing hyperglycemia. The latter complications of diabetes mellitus include microvascular complications the major microvascular complications, retinopathy and nephropathy, are the more important causes of blindness and end-stage renal disease in Europe. Different risk factors such as diabetes duration, bloo Read More

Background: Patients without a history of diabetes often develop hyperglycemia during an acute coronary syndrome (ACS). New onset of hyperglycemia (NH) is associated with higher mortality both in the short and long-term. Aim: We performed a systematic review and meta-analysis of observational studies to investigate the association between NH and mortality in patients with ACS. In-hospital, 30-day and long-term Read More

A reduced fall in nocturnal blood pressure (BP) (i.e. non-dipping) has been related to an increase in target organ damage and cardiovascular (CV) events. Numerous studies have shown that non-dipping is highly prevalent in patients with type 1 and 2 diabetes mellitus. In this paper we reviewed recent literature and our personal data on the prevalence and clinical correlates of abnormal diurnal BP rhythm in diabetic patients; in p Read More

Diabetes mellitus complicates 1-2% of all pregnancies but is associated with high a perinatal morbidity and mortality. Gestational diabetes affects up to 4% of pregnancies and is associated with foetal macrosomia (large for dates). Foetal growth is a complex process influenced by genetics, maternal factors, uterine environment and maternal and foetal hormonal status. Infants of pre-gestational diabetic mothers have an ad Read More

Some immigrant groups in Europe show an increased prevalence of diabetes, e.g. South Asians in the UK and Moroccans and Turks in the Netherlands. This study aimed at reviewing the literature among immigrants in the Nordic countries. Search was performed primarily of Medline through PubMed, and secondarily of other databases and by using information from reference lists. Terms used were: “Diabetes Mellitus Read More