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image of In Vitro Antibacterial Activity of Adiantum capillus veneris Extraction with Methanol, Chloroform, and Ether Solvents against Methicillin-resistant Staphylococcus aureus

Abstract

Background

The increasing problem of multi-drug resistant (MDR) pathogens is a worldwide concern, especially in the pharmaceutical industry. At the same time, medicinal plants have renewed interest because of their wide variety of bioactive phytochemicals, which could be used to develop new antimicrobial drugs. This renewed interest is partly due to the growing resistance to traditional drugs and their associated side effects.

Methods

The objective of this study is to assess the antimicrobial properties of the total extract and various fractions of Adiantum capillus veneris against Methicillin-resistant (MRSA). The aerial parts of were subjected to extraction using methanol, chloroform, and ether, and the resulting extracts were tested for their antimicrobial activity against MRSA. Additionally, essential oil was obtained from the aerial parts using a Clevenger apparatus and boiling water. Furthermore, Gas Chromatography-Mass Spectrometry (GC/MS) was utilized to analyze the phytochemicals isolated from the extracts of .

Results

The essential oil was obtained through distillation and then analyzed using GC/MS. The antimicrobial activity was evaluated using the agar diffusion method.

Conclusion

GC/MS analysis revealed that the composition was primarily phytol (59.9%), constituting 99.3% of phyto-constituents. However, both the total extract and the individual fractions exhibited no inhibitory effects against MRSA strains.

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2024-10-25
2025-01-13

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/content/journals/cddt/10.2174/0115701638313570241015045118
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In Vitro Antibacterial Activity of Adiantum capillus veneris Extraction with Methanol, Chloroform, and Ether Solvents against Methicillin-resistant Staphylococcus aureus
Bentham Science Publishers ; https://doi.org/10.2174/0115701638313570241015045118
/content/journals/cddt/10.2174/0115701638313570241015045118
/content/journals/cddt/10.2174/0115701638313570241015045118
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  • Article Type:     Research Article
Keywords: multi-drug resistant (MDR) ; gas chromatography-mass spectrometry (GC/MS) ; methicillin-resistant Staphylococcus aureus (MRSA) ; antimicrobial drugs ; essential oil ; Adiantum capillus veneris

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