2000

Current Drug Delivery - Volume 18, Issue 7, 2021

Volume 18, Issue 7

Volume 18, Issue 7, 2021

- Characterization of Glyoxal Modified LDL: Role in the Generation of Circulating Autoantibodies in Type 2 Diabetes Mellitus and Coronary Artery Disease
  
  Authors: Md M. Rizwee, Minhal Abidi, Safia Habib, Abdul Rouf Mir, Asif Ali and Moin Uddin
  
  https://doi.org/10.2174/1567201818666210810143548
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  Aims: This study aims to investigate the role of glyoxal modified LDL in the immunopathology of diabetes and cardiovascular disease. Background: Glycoxidation of proteins is widely studied in relation to diabetes and cardiovascular disease. Objective: This study probed the glyoxal mediated modifications in LDL, analyzed the immunogenicity of the glycated LDL and ascertained the presence of circulating antibodies against m Read More
  
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- Development and Optimization of Luliconazole Nanostructured Lipid Carriers Based Gel by Quality by Design its Skin Distribution Studies, Dermatokinetic Modeling & In-Vitro and Ex-Vivo Correlation
  
  Authors: Eranti Bhargav, Yiragamreddy P. Reddy and Kunnatur B Koteshwara
  
  https://doi.org/10.2174/1567201818666201214145818
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  Aim: The present study was aimed to improve the permeability of Luliconazole (LZ) and to localize high drug concentrations at skin layers by Quality by Design (QbD) based Nanostructured lipid carriers (NC) based gel. Methods: Quality Target Product Profile was set, and Critical Quality attributes were identified. FT-IR and DSC studies confirmed compatibility. Risk assessment was carried out by screening the factors using Read More
  
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