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2000
Volume 26, Issue 11
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

SARS-CoV-2 is a disease that endangers both human life and the economy. There was an 11- month period of relative evolutionary standstill following the appearance of SARS-CoV-2 in late 2019. However, the emergence of clusters of mutations known as' variants of concern 'with variable viral properties such as transmissibility and antigenicity defined the evolution of SARS-CoV-2. Several efforts have been made in recent months to understand the atomic level properties of SARS-CoV-2. A review of the literature on SARS-CoV-2 mutations is offered in this paper. The critical activities performed by different domains of the SARS-CoV-2 genome throughout the virus's entry into the host and overall viral life cycle are discussed in detail. These structural traits may potentially pave the way for the development of a vaccine and medication to combat the SARS-CoV-2 sickness.

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/content/journals/cchts/10.2174/1386207326666221108095705
2023-09-01
2025-07-03
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/content/journals/cchts/10.2174/1386207326666221108095705
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  • Article Type:
    Review Article
Keyword(s): COVID-19; drug; mutation; SARS-COV-2; structural component; vaccine
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