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2000
Volume 20, Issue 10
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

Aims & Scope: Computational drug repositioning emerges as a new idea of drug discovery and development. Contrary to conventional routines, computational drug repositioning encompasses low risk and high safety. Some successful cases demonstrated its advantage. Therefore, a large number of computational drug repositioning approaches have been developed over the past decades. We summarized briefly these methods and classified them into target-based, geneexpression- based, phenome-based and multi-omics-based categories according to strategies of drug repositioning. Conclusion: We reviewed some representatives of computational drug repositioning methods in each category, with emphasis on detail of techniques and finally discussed developing trends of computational drug repositioning.

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/content/journals/cchts/10.2174/1386207321666171221112835
2017-12-01
2025-07-15
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