Full text loading...
- ISSN: 1386-2073
- E-ISSN: 1875-5402
-
Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles Amicable for Automation
- Source: Combinatorial Chemistry & High Throughput Screening, Volume 16, Issue 8, Sep 2013, p. 657 - 663
-
- 01 Sep 2013
- Previous Article
- Table of Contents
- Next Article
Abstract
A three-component 3+2 cycloaddition reaction followed by Suzuki coupling reaction was carried out to synthesize a library of compounds using automation (parallel synthesizer). Scaffolds that are unexplored in literature were used for the synthesis of library. The iodo-triazoles formed by 3+2 cycloaddition reaction were coupled with boronic acids to get tri-substituted triazoles.
© Bentham Science Publishers