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- ISSN: 1386-2073
- E-ISSN: 1875-5402
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ZnO Nanoparticles-Catalyzed Cyclocondensation Reaction of Arylmethylidenepyruvic Acids with 6-Aminouracils
- Source: Combinatorial Chemistry & High Throughput Screening, Volume 16, Issue 1, Jan 2013, p. 32 - 36
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- 01 Jan 2013
Abstract
A new, efficient, and solvent-free cyclocondensation reaction of arylmethylidenepyruvic acids with 6- aminouracils is presented that uses a catalytic amount of ZnO nanoparticles (ZnO Nps) as a recyclable catalyst at 70 °C. This protocol has the advantages of high yields (91-98%), easy work-up, very short reaction time (2 h), and using environmentally friendly procedure.
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