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2000
Volume 15, Issue 5
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

A simple one-pot method for the preparation of 7-amino-2,4-dioxo-5-aryl-1,2,3,4-tetrahydropyrido[2,3- d]pyrimidine-6-carbonitriles 4 from aromatic aldehydes, malononitrile and 4(6)-aminouracil in the presence of ZrO2 nanoparticles (ZrO2 NPs) as an efficient heterogeneous catalyst is described. The procedure has the advantages of high yields (86-97%), short reaction time (2h) and an environmentally friendly specificity....

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/content/journals/cchts/10.2174/138620712800194486
2012-06-01
2025-07-12
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