Skip to content
2000
Volume 12, Issue 9
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

Over the last decade, imaging as a detection mode for cell based assays has opened a new world of opportunities to measure “phenotypic endpoints” in both current and developing biological models. These “high content” methods combine multiple measurements of cell physiology, whether it comes from sub-cellular compartments, multicellular structures, or model organisms. The resulting multifaceted data can be used to derive new insights into complex phenomena from cell differentiation to compound pharmacology and toxicity. Exploring the major application areas through review of the growing compendium of literature provides evidence that this technology is having a tangible impact on drug discovery and the life sciences.

Loading

Article metrics loading...

/content/journals/cchts/10.2174/138620709789383277
2009-11-01
2025-07-07
Loading full text...

Full text loading...

/content/journals/cchts/10.2174/138620709789383277
Loading
This is a required field
Please enter a valid email address
Approval was a Success
Invalid data
An Error Occurred
Approval was partially successful, following selected items could not be processed due to error
Please enter a valid_number test