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Volume 12, Issue 2
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

Hyphenation with liquid chromatography has become indispensable in mass spectrometry-based proteomics. Sample complexity together with the large variations in dynamic range can be only tackled using techniques that isolate and/or concentrate individual components prior to mass spectrometric analysis. In this review the most recent developments in micro/nanoliquid chromatography interfaced with MALDI and electrospray ionisation are discussed. Particular attention is focused on all applications related to quantitative proteomics.

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/content/journals/cchts/10.2174/138620709787315418
2009-02-01
2025-07-08

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  • Article Type:     Research Article
Keyword(s): electrospray ionisation; Liquid Chromatography; MALDI; Mass Spectrometry; proteomics

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