A Decade of Yeast Surface Display Technology: Where Are We Now?

Eric V. Shusta; Lauren R. Pepper; Yong K. Cho; Eric T. Boder

doi:10.2174/138620708783744516

ISSN: 1386-2073
E-ISSN: 1875-5402

A Decade of Yeast Surface Display Technology: Where Are We Now?
Authors: Eric V. Shusta¹, Lauren R. Pepper², Yong K. Cho³ and Eric T. Boder⁴
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¹ Department of Chemical and Biological Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, WI 53706, USA. ² Department of Chemical and Biological Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, WI 53706, USA. ³ Department of Chemical and Biological Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, WI 53706, USA. ⁴ Department of Chemical and Biological Engineering, University of Wisconsin-Madison, 1415 Engineering Drive, Madison, WI 53706, USA.
Source: Combinatorial Chemistry & High Throughput Screening, Volume 11, Issue 2, Feb 2008, p. 127 - 134
DOI: https://doi.org/10.2174/138620708783744516
- Available online: 01 Feb 2008

Abstract

Yeast surface display has become an increasingly popular tool for protein engineering and library screening applications. Recent advances have greatly expanded the capability of yeast surface display, and are highlighted by cellbased selections, epitope mapping, cDNA library screening, and cell adhesion engineering. In this review, we discuss the state-of-the-art yeast display methodologies and the rapidly expanding set of applications afforded by this technology.

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2008-02-01

2025-07-19

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Article Type: Research Article

Keyword(s): library screening; protein engineering; Yeast surface display

A Decade of Yeast Surface Display Technology: Where Are We Now?

Abstract

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