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2000
Volume 8, Issue 5
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

selected 4-thiazolidinone have been synthesized and tested as anti-HIV activity. The results of the in vitro tests showed that one of the compounds, 5, inhibited the enzyme at 0.204μM concentration with minimal toxicity to MT-4 cell. Furthermore, the QSAR studies indicated the role of PMIZ, Ovality and Total energy content of the compounds in rationalizing the activity.

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/content/journals/cchts/10.2174/1386207054546496
2005-08-01
2025-06-27
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