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- ISSN: 1386-2073
- E-ISSN: 1875-5402
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The Use of a Supported Base and Strong Cation Exchange (SCX) Chromatography to Prepare a Variety of Structurally-Diverse Molecular Libraries Prepared by Solution-Phase Methods
- Source: Combinatorial Chemistry & High Throughput Screening, Volume 5, Issue 3, May 2002, p. 211 - 218
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- 01 May 2002
Abstract
The preparation of molecular libraries of aminomethylbiaryls, allylic amines, and ethanolamines using solution-phase methodology is described. In particular, the use of a solid-supported base reagent (PTBD resin) and strong cation exchange(SCX) resin to effect ‘catch and release’ purification across these diverse libraries is highlighted.
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