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2000
Volume 5, Issue 6
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

Combinatorial chemistry has become a dramatically useful tool for the development of new medicinal agents. In the search to discover a novel and effective lead for the treatment of giardiasis, solutionphase synthesis of a library of isoflavone derivatives has been accomplished. Of the products screened, several compounds such as P(A1,B1) and P(A1,B11) exhibited potent antigiardial activity. The details of synthesis, in vitro antigiardial assay, and preliminary structure-activity relationships of these compounds are described.

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/content/journals/cchts/10.2174/1386207023330138
2002-09-01
2025-07-05
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