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2000
Volume 5, Issue 7
  • ISSN: 1386-2073
  • E-ISSN: 1875-5402

Abstract

A simple and fast one-pot method using microwave irradiation for the synthesis of a number of small libraries of diverse heterocycles is described in this paper. The two-step one-pot method includes the formation of alkylaminopropenones or alkylaminopropenoates in 5 min at 180 °C and a subsequent treatment with dinucleophiles for 3 to 5 min at 150 °C to 180 °C to form a variety of biologically interesting heterocycles in a cascade-type reaction. The combination of combinatorial chemistry and microwave-assisted synthesis was found to be very efficient.

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/content/journals/cchts/10.2174/1386207023330048
2002-11-01
2025-07-11
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