Current Chromatography - Volume 5, Issue 2, 2018

Background: Since the 1990s, technical developments and theoretical studies of columns packed with core-shell and sub-core-shell particles demonstrated improved efficiency separation, time reduction, solvent use than fully porous columns. Thanks to this chromatographic system, environmental pollutants are being analysed under green conditions. Objective: This paper presents theoretical aspects and a review of Read More

Different nanoparticles have successfully been used in laboratory, pilot and field scale for degradation of organic dangerous pollutants during the last decades. In fact, nanotechnology will, in the near future, play a key role in soil and ground/wastewater decontamination chemical processes. However, since many of the developed techniques for this purpose are still at an experimental or pilot stage, there is a need to demonst Read More

Background: Dehydroleucodine is a sesquiterpene lactone isolated from Artemisia douglasiana Besser. Distinctive biological and pharmacological activities have been shown extensively for this molecule. Only one analytical method has been described for the quantification of dehydroleucodine in biological experimental systems. However, this assay involves fluorescent detection that is normally not recommended for routine an Read More

Background: Testing of hair samples for drugs of abuse is advantageous as compared to other complementary matrices like urine or blood, due to longer detection window, non-invasive, and easy storage conditions. Ethyl glucuronide (EtG) is a promising biomarker for the identification of alcohol abuse in doping control or forensic analysis. Objective: This paper introduces a fast and sensitive method for determination of Et Read More

Background: Voriconazole (VORI), a derivative of fluconazole, shows a greater selectivity for the fungal enzyme than for the corresponding rat liver enzyme as compared to Ketoconazole and Itraconazole. Methods: An environment friendly, simple, rapid, and isocratic robust supercritical fluid chromatographic method has been developed and validated for determining Voriconazole (VORI) in Bulk drug and laboratory mixture re Read More