Current State of ERG as Biomarker in Prostatic Adenocarcinoma

Balazs Acs; Tibor Szarvas; Nora Szekely; Peter Nyirady; A. Marcell Szasz

doi:10.2174/156800961508151001100829

ISSN: 1568-0096
E-ISSN: 1873-5576

Current State of ERG as Biomarker in Prostatic Adenocarcinoma
By Balazs Acs, Tibor Szarvas, Nora Szekely, Peter Nyirady and A. Marcell Szasz
Source: Current Cancer Drug Targets, Volume 15, Issue 8, Oct 2015, p. 643 - 651
DOI: https://doi.org/10.2174/156800961508151001100829
- Available online: 01 Oct 2015

Abstract

In this review we briefly discuss the possible biomarkers of prostate cancer among them we focus and analyze the relevance of TMPRSS2-ERG fusion gene in line with ERG expression in the diagnosis of prostate cancer. Starting at diagnosis and genetic alterations in prostate carcinomas, we examine the incidence and detection of the most common genetic aberration in this tumor and its protein product as well. We also examined the correlation of clinicopathological factors and prognosis with ERG and the TMPRSS2-ERG fusion oncogene and ERG expression as predictive markers.

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2015-10-01

2025-05-30

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Article Type: Research Article

Keyword(s): Diagnosis; ERG; prediction; prognosis; prostate carcinoma; TMPRSS2

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Current State of ERG as Biomarker in Prostatic Adenocarcinoma

Abstract

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