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2000
Volume 4, Issue 3
  • ISSN: 2212-7968
  • E-ISSN: 1872-3136

Abstract

Virus-like particles (VLPs) are viral coats formed by the self-assembly of the components of viruses excluding their genetic material. These particles may be used as vectors to transport molecules chemically attached on the VLP surface, or as vessels for the systemic delivery of pharmacologically important molecules as drugs, siRNAs, genes, mRNAs, magnetic nanoparticles, quantum dots and other medical-imaging aids. Herein we review the recent advances in heterologous production and purification of VLPs, the current trends in chemical modification of VLPs, and the advances on the application of VLPs as vectors, tools for medical imaging and materials for nanotechnology.

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/content/journals/ccb/10.2174/2212796811004030231
2010-09-01
2025-07-04
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/content/journals/ccb/10.2174/2212796811004030231
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  • Article Type:
    Research Article
Keyword(s): drug delivery; gene delivery; imaging; nanomaterials; nanomedicine; Virus-like particles
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